Structure of PDB 8cst Chain X Binding Site BS01

Receptor Information
>8cst Chain X (length=352) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AISRTNENDPAKHGDQHEGQHYNISPQDLETVFPHGLPPRFVMQVKTFSE
ACLMVRKPALELLHYLKNTSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCA
KQDWLILHIPDAHLWVKNCRDLLQSSYNKQRFDQPLEASTWLKNFKTTNE
RFLNQIKVQEKYVWNKRESTEKGSPLGEVVEQGITRVRNATDAVGIVLKE
LKRQSSLGMFHLLVAVDGINALWGRTTLKREDKSPIAPEELALVHNLRKM
MKNDWHGGAIVSALSQTGSLFKPRKAYLPQELLGKEGFDALDPFIPILVS
NYNPKEFESCIQYYLENNWLQHEKAPTEEGKKELLFLSNANPSLLERHCA
YL
Ligand information
>8cst Chain A (length=888) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaacucaccugaguuguaaaaaacuccaguuga
cacaaaauagacuacgaaaguggcuuuaacauaucugaacacacaauagc
uaagacccaaacugggauuagauaccccacuaugcuuagcccuaaaccuc
aacaguuaaaucaacaaaacugcucgccagaacacuacgagccacagcuu
aaaacucaaaggaccuggcggugcuucauaucccucuagaggagccuguu
cuguaaucgauaaaccccgaucaaccucaccaccucuugcucagccuaua
uaccgccaucuaacccugaugaaggcuacaaaguacguuaggucaaggug
uagcccaugagguggcaagaaaugggcuacauuuucuaccccagaaaacu
acgauagcccuuaugaaacuuaagggucgaagguggauuuagcaguaaac
ugagaguagagugcuuaguugaacagggcccugaagcgcgucacccuccu
caaguauacuucaaaggacauuuaacuaaaaccccuacgcauuuauauag
aggagacaaguaaguguacuggaaagugcacuuggacg
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<....<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>.........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<......<<<.<<<.<<<......>>>..>>>.>>>
.............<<....>>.>>>>>>.....>>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<....>>>>
.....>>..>>>>>>......<<<<<<<...<<<.<<<<<..<<<<<<<<
.......<<........>>..........<<<<<<<.......<<.<<<.
.<<.<<<<.<..<<<<<.....>>>.......>>..>.>.>>>....>>>
>>>>....>>>>>>>.....>>>>>>>>.....<<<<.....>>>>....
.<....<<<<<<<.......>>>>>>>....>.....>>>>>.....<<<
<<<<.........>>>>>>>.....>>>...>>>>>>>.......<<<<<
<..<<<<<......<<<....<<.....>>...>>>.......>>>>>.>
>>>>>......<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB8cst Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		K130 N164 T313 F317 K318 R320 S389 R393
Binding residue
(residue number reindexed from 1)		K84 N118 T267 F271 K272 R274 S343 R347
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006915 apoptotic process
GO:0032543 mitochondrial translation
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8cst, PDBe:8cst, PDBj:8cst
PDBsum8cst
PubMed36482135
UniProtP51398|RT29_HUMAN Small ribosomal subunit protein mS29 (Gene Name=DAP3)

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