Structure of PDB 8c00 Chain X Binding Site BS01

Receptor Information
>8c00 Chain X (length=141) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYI
DKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRH
KNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAA
Ligand information
>8c00 Chain 2 (length=1425) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaaauacagugaaacugcgaauggcucauuaa
aucaguuaucguuuauuugauaguuacaugguauaacugugguaauucua
gagcuaauacaugcuuaaaaucucgaagagauguauuuauuagauaaaaa
auugaugauucauaauaacuuuucgaaucgcauggccgcuggcgaugguu
cauucaaauuucugcccuaucaacuuucgaugguaggauaguggccuacc
augguuucaacggguaacggggaauaaggguucgauuccggagagggagc
cugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuacc
caauccuaauucagggagguagugacaauaaauaacgauacagguuguau
uggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggcaag
ucuggugagcagccgcggauuccagcuccaauagcguauauuaaaguugu
ugcaguuaaaaagcucguaguugaacuuugggcccgguuggccaacgggg
ccuuuuuuacuuugaaaaaauuagaguguucaaagcaggcgugcucgaau
auauuagcauggaauaauagaauaggacguuugguucuauuuuuuucuag
gaccaucguaaugauuaauagggacggucgggggcaucaguauucaauug
ucagaggugaaauucuuggauuuauugaagacuaacuacugcgaaagcau
uugccaaggacguuuucauuaaucaagaacgaaaguuaggggaucgaaga
ugaucagauaccgucguagucuuaaccauaaacuaugccgacuagggauc
gggugguguuuuuaaugacccacucggcaccuuacgagaaaucaaagucu
uuggguucuggggggaguauggucgcaaggcugaaacuuaaaggaauuga
agggcaccaccaggaguggagccugcggcuuaauuugaaacucaccaggu
ccacacaauaagauugacagauugagagcuuucuugauuugugguagugg
ugcuagcaugcuggucacuguucugggcgcacgcgcgcuacacugacgga
gccagcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuc
cgucgugcuggggauagagcauuguaauuauugcucuucaacgaggaauu
ccuaguaagcgcaagucaucagcuugcguugauuacgucccugcccugua
ccuaguaccgauugaauggcuuagugaggccucaggaucugcuuagaguc
agagcggagaauuuggacaaacuuggucauuuagaggaacuagguuuccg
uaggugaaccugcggaaggaucauu
..<<<<<.[[((((>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<.......>>...>>.>>......<<......
..<<<..<<..<<....<<<........<<......<<.<<<.....>>>
.>>......>>........<<<<<...>>>>><.<.<<<<<<......((
(...........>>>>>>.>...>...<<<<..<<<.>>>.>>>>....>
>>...>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>
>>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<
..........>>>.>>.<.<<....>>.>...>>>>>>.........<<<
....<<<.....>>>..>>>..>....>.>.....<<<<<<<<.>>>>>>
>>......<<..<...........>..>>.........<<<<<((....<
.<<<<...<<..))>>.....>>>>>>>>>>..>>>>>>>>>>.......
..<<<[[.....<.<<...<<<.<<....<<<<<<.<<<<..>>>>.>>>
>>>...<<<<<.<<.......<<...<.......>..<<<..>>>....>
>......>>.>>..>>>.........<<<..<<<<<<<<....))).>>>
>>>>>.>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<
...<<<..(...>>>......>.>>>>>>..>>.......<<....>>..
.>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<
<<..)......>>>>...>>>>>>>>..........<<<.<<.<<<..<<
<<<<<<.<<<......>>>>>>>>>>>..>>>...<<..]]>>...>>..
...>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]]..
<<<<<<..<<..<<<<<..<<<.<<<<<<...............<<<<<.
<..<<<<<.......<<.<<........>>.>>.....>>>>>..<<<<.
.<<<<<<..>>>>>>>>>>>.>>>>>..>>.>>>>.>>>.....<<<<<<
<......<<.....<<..<<<<....>>>>..>>....>>.......>>>
>>>>......<....<<<<<<..........>>>>>>....>.....>>>
>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>...
..<<<..<<....<<<<<<<<.<<<..<.<<..<...<<<<<<.......
..>>>>>>...>..>>.>..>>>.>>>>>>>>...>>..>>>...<<<<<
<<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c00 Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H18 W34 G39 L40 K57 S65 I66 R67 K69 M80 Y90 H92 K96 Y97 R103 H104 N106 R129 P130 S132 K133 T134
Binding residue
(residue number reindexed from 1)		H14 W30 G35 L36 K53 S61 I62 R63 K65 M76 Y86 H88 K92 Y93 R99 H100 N102 R125 P126 S128 K129 T130
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8c00, PDBe:8c00, PDBj:8c00
PDBsum8c00
PubMed36996028
UniProtP0CX47|RS11A_YEAST Small ribosomal subunit protein uS17A (Gene Name=RPS11A)

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