Structure of PDB 7ttu Chain X Binding Site BS01 |
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| >7ttu Chain 1 (length=2684)
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uaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaa
ggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugau
ccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucg
auaugugaauacauagcauaucagaaggcacacccggagaacugaaacau
cuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggcg
agcgaaacgggaagagcccaaaccaacguugggguuguaggacacucuag
uuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaag
guaauaauccuguagucgaaaauguugucucucuugaguggauccugagu
acgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaa
ggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaag
gugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcu
uacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaau
gaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagcc
guagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccg
aaaccaggugaucuacccuuggucagguugaaguucagguaacacugaau
ggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggua
gcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauag
cuuuagggcuagccucaagugaugauuauuggagguagagcacuguuugg
acgagcgaauucagacaaacuccgaaugccaauuaauuuaacuugggagu
cagaacaugggugauaagguccguguucgaaagggaaacagcccagacca
ccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguugc
cacagagugacacugcgccgaaaauguaccggggcuaaacauauuaccga
agcuguggauugucgacaaugguaggagagcguucuaagggcguugaagc
augaucguaaggacauguggagcgcuuagaagugagaaugccggugugag
uagcgaaagacgggugagaaucccguccaccgauugacuaagguuuccag
aggaaggcucguccgcucuggguuagucggguccuaagcugaggccgaca
ggcguaggcgauggauaacagguugauauuccuguaccaccuauaaucgu
aucgauggggggacgcaguaggauaggcgaagcgugcgauuggauugcac
gucuaagcaguaaggcgcugagcugugauggggagaagaccuucgagucg
uugauuucacacugccgagaaaagccucuagauagaaaauaggugcccgu
accgcaaaccgacacagguagucaagaugagaauucuaaggugagcgagc
gaacucucguuaaggaacucggcaaaaugaccccguaacuucgggagaag
gggugcucuuuaggguuaacgcccagaagagccgcagugaauaggcccaa
gcgacuguuuaucaaaaacacaggucucugcuaaaccguaaggugaugua
uaggggcugacgccugcccggugcuggaagguuaagaggagugguuagcu
ucugcgaagcuacgaaucgaagccccaguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgacccgcacga
aaggcguaacgauuugggcacugucucaacgagagacucggugaaaucau
aguaccugugaagaugcagguuacccgcgacaggacggaaagaccccgug
gagcuuuacuguagccugauauugaaauucggcuuucuaacccgcaccac
uuaucguggugggagacagugucaggcgggcaguuugacuggggcggucg
ccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguugga
aaucauucauagaguguaaaggcauaagggagcuugacugcgagaccuac
aagucgagcagggucgaaagacggacuuagugauccggugguuccgcaug
gaagggccaucgcucaacggauaaaagcuaccccggggauaacaggcuua
ucucccccaagaguucacaucgacggggagguuuggcaccucgaugucgg
cucaucgcauccuggggcuguagucggucccaaggguugggcuguucgcc
cauuaaagcgguacgcgagcuggguucagaacgucgugagacaguucggu
cccuauccgucgugggcguaggaaauuugagaggagcuguccuuaguacg
agaggaccgggauggacauaccucugguguaccaguugucgugccaacgg
cauagcuggguagcuauguguggacgggauaagugcugaaagcaucuaag
caugaagccccccucaagaugagauuucccaacuucgguuauaagauccc
ucaaagaugaugagguuaauagguucgagguggaagcauggugacaugug
gagcugacgaauacuaaucgaucgaagacuuaau |
<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<......
<<<<<<.[...((.>>>.....<<<<<<<..<<.))...]..>>.....>
>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<
<<<<<<.........>>>>>>>.>>.>>....<<<<<......<<....>
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<..>>>>......<<<<<.......
........<.<<<<<<<.<<<...<<<<<......>>>>>((......<<
<.....))>>>...>>>...>>>>>>>..>.........>..>>>>....
.<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..
)))......]].>>>>>>>.]]...............<<....>>....]
].........<<<<....>>>>.............}....>>>>>>>>>>
>.......<<<<..<<<<......>>>>..>>>>...<.<........>.
>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<
...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>
.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>.
..<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<
<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<<
<........>>>>>>>>..>>.>.....>>>>.>>>>>..>>>>>>>.>>
..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<
<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<.<<.
.......>>.>.>>>>.>>...........))).....>>>>>>.>>>..
.>>>>>>><<<<<..>>>>>....>>>>>><.<<<<<<<.<<......<<
<<<.<<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><....
..<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<
<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....
>>>...>>>...>>...<<<<<........>>>>>))<<<<<<.......
.<<...<<<<....<<<<...<<...<......<<<.........>>>..
.<....<<<<...<<..>>...>>>>.....>..................
.>....>>...>>>>.........>>>>..>>.......>>>>>>>>>>.
.>>.....<<......>>>>>>>.<<<.......>>>..>>>>..<<<<.
...<<<<<<<<.<<...............<<<<<....<<..>>.....>
>>>><<<<<<<.<<<<....>>>>.>>>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<......>>......
.>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<<<<<.<<.
...>>..>>>>>>...>>..>>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<<.....>>>>>>.....>..
..>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>.>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<<<<<<..<<<<......>>>>....<<.<<<<<<
.....>>>>>>>>......>>>>>>>>..>>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.....
..>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<....
..>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>
>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.<
.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<
<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>
>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>...
.]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.......
........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<....>>>>
>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>
>>>....>>>.>>>>.......>>>>>>>.<<<....>>>....<<<<<<
<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>.
..>>>..>>>>>.>>>...>>>>....>>>>>.. |
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| PDB | 7ttu A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | H4 L6 K7 G11 S12 K14 R18 G20 R21 A24 T25 G28 K29 T30 S31 G32 R33 H35 K36 G37 Q38 R41 S42 G43 F50 G52 G53 Q54 R59 R60 P62 K63 R64 G65 F66 T67 N68 R71 K72 I76 K103 K110 L112 G113 N114 A130 S131 |
Binding residue
(residue number reindexed from 1) | H3 L5 K6 G10 S11 K13 R17 G19 R20 A23 T24 G27 K28 T29 S30 G31 R32 H34 K35 G36 Q37 R40 S41 G42 F49 G51 G52 Q53 R58 R59 P61 K62 R63 G64 F65 T66 N67 R70 K71 I75 K102 K109 L111 G112 N113 A129 S130 |
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| Enzyme Commision number |
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