Structure of PDB 7ryg Chain X Binding Site BS01

Receptor Information
>7ryg Chain X (length=60) Species: 480119 (Acinetobacter baumannii AB0057) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTKDLREKSVEELKALLDEQQLNQFRLRMAKATGQLGKSHEVQVARKTIA
RIKTLLTEKQ
Ligand information
>7ryg Chain A (length=2685) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaaguaauuaagugcaugugguggaugccuuggcagucagaggcgaug
aaagacgugauagccugcgaaaagcuccggggaggcggcaaauauccuuu
gauccggagaugucugaaugggggaacccaccuacuuuaagguagguauu
gcaacaugaauacauaguguugcaaggcgaacgaggggaagugaaacauc
ucaguacccuuaggaaaagaaaucaauugagauucccucaguagcggcga
gcgaacggggaucagcccauuaaguuauguguguuuuaguggaacgcucu
gggaagugcgaacguagagggugauauucccguacacgaaagggcacaca
uaaugaugacgaguagggcgaggcacgugaaaccuugucugaauaugggg
ggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccagu
accgugagggaaaggcgaaaagaaccccugugaggggagugaaauagauc
cugaaaccgcaugcauacaagcagugggagcaccuucguggugugacugc
guaccuuuuguauaaugggucagcgacuuauauucaguagcgagguuaac
cguauaggggagccguagagaaaucgagucuuaauagggcguuuaguugc
uggguauagacccgaaaccaggcgaucuauccaugagcagguugaagguu
ggguaacacuaacuggaggaccgaacccacugucguugaaaagccagggg
augacuuguggauaggggugaaaggcuaaucaagccuggugauagcuggu
ucuccccgaaagcuauuuagguagcgccucggacgaauaccauagggggu
agagcacuguuucggcaccgaugcaaacuccgaauaccuaugaguacuau
ccgggagacagacugcgggugcuaacguccguagucaagaggaaaacaau
ccagaccgccagcuaaggccccaaaaucauaguuaagugggaaacgaugu
gggaaggcauagacagcuauagucgagucggccugcgcggaagauguaac
ggggcuaaaacuaugugccgaagcugcggauguauacuuuguauacgugg
uaggggagcguucuguaagccgaugaagguguguugagaagcaugcugga
gguaucagaagugcgaaugcugacgugaguaacgacaaaacgggugaaaa
acccguucgccgaaagaccaaggguuccaguccaacguuaaucggggcug
ggugagucgaccccuaaggcgaggccgaaaggcguagucgaugggaaaau
gguuaauauuccauuacuucuguguaaugcgaugagaggacggagaaggc
uaaaucagccuggcguugguuguccaggugaaaggauguaggcaaugcug
agaucugauagcaagcuguacuugugcagcgaagugguugaugccaugcu
uccaggaaaagucucuaagcuucaguuacacaggaaucguacccgaaacc
gacacagguggucaggucgaguagaccaaggcgcuugagagaacucugcu
gaaggaacuaggcaaaaugguaccguaacuucgggagaagguacgcuguu
guuggugauggaacucgcuuccugagcugacgacagccgcagaaaccagg
ccgcugcaacuguuuauuaaaaacauagcacucugcaaacacgaaagugg
acguauagggugugaugccugcccggugcuggaagguuaauugauggggu
uagcguaagcgaagcucuugaucgaagccccaguaaacggcgccuaaggu
agcgaaauuccuugucggguaaguuccgaccugcacgaauggcauaauga
uggcggcgcugucuccagcagaggcucagugaaaucgaaaucgcugugaa
gaugcaguguacccgcggcuagacggaaagaccccgugaaccuuuacugc
agcuugacacugaacuuugauugagguucuaacucugucccgugauccgg
gacgaggaccgugucugguggguaguuugacuggggcggucuccuccuaa
agaguaacggaggaguacgaaggugcgcucagcguggucggaaaucacgc
guagaguauaaaggcaaaagcgcgcuuaacugcgagacccacaagucgag
cagguacgaaaguaggucuuagugauccggugguucuguauggaagggcc
aucgcucaacggauaaaagguacucuggggauaacaggcugauaccgccc
aagaguucauaucgacggcgguguuuggcaccucgaugucggcucaucuc
auccuggggcugaagcaggucccaaggguauggcuguucgccauuuaaag
agguacgcgagcuggguuuagaacgucgugagacaguucggucccuaucu
accgugggcgcuggaaauuugagaggaucugcuccuaguacgagaggacc
agaguggacgaaccucugguguaccgguugugacgccagucgcaucgccg
gguagcuauguucggaagggauaaccgcugaaagcaucuaagcgggaagc
cuaccucaagauaagauuucccuaggacuuuauguccucuaaagagccgu
ucgagacuaggacguugauagguuggauguggaagcauagugauauguga
agcugaccaauacuaauugcucgugaggcuugacu
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<....(((.>>>.....<<<<<<<..<<.)))......>>...
..>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...<<<......<<<<<<<<<<<<<<.<<<...<<<.<.
.....>.>>>((......<<<.....))>>>...>>>...>>>>>>>>>>
>>>>...........<<<<<<<<.........>>>>>>>>......<<<<
<..<<<<>>>>>..>>>......]].>>>>>>>.]]..............
.<<....>>....]].........<<<<.....>>>>.............
}....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>
...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<
<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>
>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<
<<......>>>>>>.....>>>...<<<.<<<.<........>.>>>>>>
....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>.
.<<<<<<....<<<<<....>>>>>.<<<<<<<....<<<<<<<<<....
.<<<...<<<.<<<<..>>>>.>>>..>>.>.....>>>>>>.>>>...>
>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<......>
>>...<<<<.<<<...<<<(((.....<<<<<<...........<<.<<<
<<<..<<.........<<..>>.....>>..>>>>>>>>...........
)))......>>>>>>.>>>...>>>>>>><<<<<<<.....>>>>>>>..
..>>>>>><.<<<<<...<<<......<<<<<<<<....>>>>>>>>...
>>>..>>>>>..>.....>>>>>><......<<.....<<<<<<......
.>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>
>....((<<<.<<<...<<<...<<<....>>>...>>>...>>>..<<<
<<........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<..<<<
..<<<<<<<<<<<...((((...>>>>>>....<<<<...<<<<.>>>>.
..>>>>........<<<<<......>>>>>....>>>>>...>>>...>>
>>.........>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<
......>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<
<.<<...............<<<<<.....<..>......>>>>><<<<<<
<<<<<<...<<<<.....>>>>...>>>>>>>>>>>>............<
<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.
......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<........<<<<<
..<<....>>...>>>>>........>>>>>>>>..>>>>>.........
.<...........<<<<<<.....>>>>>>.....>....>>>>>..>>.
>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<....
....>>>>>..<<<<<<<.<<<<.[[......<<<<.[[<<<<..<<<<.
.<<<.<<<<<.<<<<<<<<..>>>>>>>>...<<<.<<<<<<.....>>>
>>>>>>....>>>>>.>>>...>>>>..<<<<.....>>>><<<<<<...
........>>>>>>..<<...<<<<<<<..<<<<<<<.......>>>>>>
.>...<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>
>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>
>>>>.............>>>>..]]>>>>.......<<<<.<.<<<<<<.
..<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<
..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>
>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..>>>
>>>>>>>>....<<<<<<<...<<<<..<<<<<<................
.>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>
>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>
>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<<<<<<
<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>..
.>>...>>>>>.>>>...>>>>..>..>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ryg An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii.
Resolution2.38 Å
Binding residue
(original residue number in PDB)		R7 R47 K48 R52 K54 T55 T58
Binding residue
(residue number reindexed from 1)		R6 R46 K47 R51 K53 T54 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ryg, PDBe:7ryg, PDBj:7ryg
PDBsum7ryg
PubMed35100868
UniProtB7IA31|RL29_ACIB5 Large ribosomal subunit protein uL29 (Gene Name=rpmC)

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