Structure of PDB 7pmk Chain X Binding Site BS01

Receptor Information
>7pmk Chain X (length=665) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADFSLTVLRARIALLATAIGGPDYTPPYKLGDDCLACLKDLKRWFKLVDD
QQKRWDVAMAVAEYRILTDDLLPILIDWENKCSLAAKLANKAYYDKIALN
CLQLLVLMTWPLIVTEQSSSNQITLYGELKKHQLVYKKTILSMESGKVLR
AAIRLALDVIKIDRLSRTPRDNMVLKLVLNFFRNVIAIEPGEFTINTKKS
MPKKGITSIDTLPPNVSMDDISLNTVISSFHKNKVFGFLLTLTSSLSDFI
NIPLLEIMFYFTKDVNQELLFPRTSAGFELSKLLQKEHQMRKNVIKHTSA
RHSRFGGLLSIQTPDKTRLTVSGSQALVDEKIALQKLDDSKKWNKRIIKK
EGLPNSLLNSQTGKAIFFTESNGKHFKEFINNFIDSGFNILLHSVTNYFT
TEQDRMVTLEQVEYLLFFAWFVKYQLLRSKIDNSADIKQVSEALKEVTFI
LVSSLLRSAYDLKNWTVTHAGMIAFNELLNLVSRTKAAQDIEFIVSRLFS
DERIQLLSNLPKIGSKYSLQFMKSCIELTHSVLKVLEQYSVNFQKVQANY
MTEPVIETYINFLERFRELEDDSIKKVFSFFHRVFVQAKEQALLFRFDLI
ILLREMLSPDGLDRMSRSRKYVSQFSDYFLARLKKRLKKSPAWFVGLLFP
PLHNSEVGFYQRYGE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pmk A conserved mechanism for regulating replisome disassembly in eukaryotes.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R401 K404 H769
Binding residue
(residue number reindexed from 1)		R346 K349 H653
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000076 DNA replication checkpoint signaling
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0007064 mitotic sister chromatid cohesion
GO:0008156 negative regulation of DNA replication
GO:0031297 replication fork processing
GO:0043111 replication fork arrest
GO:0043570 maintenance of DNA repeat elements
GO:0051321 meiotic cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0031298 replication fork protection complex
GO:0043596 nuclear replication fork

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pmk, PDBe:7pmk, PDBj:7pmk
PDBsum7pmk
PubMed34700328
UniProtP53840|TOF1_YEAST Topoisomerase 1-associated factor 1 (Gene Name=TOF1)

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