Structure of PDB 7nad Chain X Binding Site BS01

Receptor Information
>7nad Chain X (length=98) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKALKVRTSATFRLPRLDSYKVIEQPITSETAMKKVEDGNILVFQVSMKA
NKYQIKKAVKELYEVDVLKVNTLVRPNGTKKAYVRLTADYDALDIANR
Ligand information
>7nad Chain 1 (length=697) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augccugaauagggugaagccagaggaaacucugguggaggcucgcgaau
uuggguauaguagcaaauauucaaaugagaacuuugaagacugaaguggg
gaaagguuccacgucaacagcaguuggacguggguuagucgauccuaaga
gaugguuucaaaggccugacaggccaccaucgaaagggaauccgguuaag
auuccggaaccuggauauggauucuucacgguaacguaacugaaugugga
gacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcuua
ucaccccggaauugguuuauccggagauggggucuuauggcuggaagagg
ccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaaucca
caggaaggaauaguuuucaugccaggucguacugucuccaaggugaacag
ccucuaguugauagaagauaagggaagucgguccguaacuucgggauaag
gauuggcucuaagggucggguagugagggccuuggucacggccuuggcuu
gcuacaauuaacgaucaacuuagaacugguacggacaaggggaaucugac
uguuaacgagauucccacugucccuaucuacuaucuagcgaggcugucug
aucaggcauugcguaagcaguagaguagccguuacgaucugcugaga
<<<<<<<<...<<<....<<<<<<<....>>>>>>>.....>>>......
>>>>>>>>....<<.....<<<<<<.......>>>>>><<<<.....<<<
<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<
............<<<<<<.>>>>>>....>>....>>...<<<<<.....
...>>>>>))<<<<.<<<<<<......<<<....>>>.......<<<<<<
...<<<<.<<<<<<<.<<<<<<<<<<..(((..>>>>>><...<<<<<..
..<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<
<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>
>>............>>.>>>>>>>>>>>>..>>.>>>>>.<<<<.....>
>>>..>>>>..<<<<.<<<<.<<........<<<<<<.<<<<........
.............<<<<<.<<<<<<<<..<<..<<<<..>>>>..>>>>>
>>>>>......>>>>>......>>>...>>>>>>>....<<<<<<<<<..
......>>.>>>>>>>.....>>.>>>>.....>>>>>>...<<<<<<<)
)).>>>>>..>>....<<<<....<<.......>>...>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nad Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.04 Å
Binding residue
(original residue number in PDB)		T31 F32 R33 L34 P35 S69 K75 N91 K92 Y93 K109 N111 L113 V114 P116 K120 K121 Y123 R125
Binding residue
(residue number reindexed from 1)		T11 F12 R13 L14 P15 S29 K35 N51 K52 Y53 K69 N71 L73 V74 P76 K80 K81 Y83 R85
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nad, PDBe:7nad, PDBj:7nad
PDBsum7nad
PubMed36482249
UniProtP04456|RL25_YEAST Large ribosomal subunit protein uL23 (Gene Name=RPL25)

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