Structure of PDB 6am3 Chain X Binding Site BS01

Receptor Information
>6am3 Chain X (length=135) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLK
KEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMY
EDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6am3 Chain X Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6am3 High-resolution structure of RGS17 suggests a role for Ca2+in promoting the GTPase-activating protein activity by RZ subfamily members.
Resolution1.53 Å
Binding residue
(original residue number in PDB)		Y106 E109
Binding residue
(residue number reindexed from 1)		Y35 E38
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6am3, PDBe:6am3, PDBj:6am3
PDBsum6am3
PubMed30940727
UniProtQ9UGC6|RGS17_HUMAN Regulator of G-protein signaling 17 (Gene Name=RGS17)

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