Structure of PDB 5z3g Chain X Binding Site BS01

Receptor Information
>5z3g Chain X (length=202) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSNFVKQLSSNNRKTRVNALEALKKYLTAKQIEFNKLWKGLYYAMWFSDR
PRPQQRLANELGELHGLTTNDKAFIKFSRGFWKVMCFEWFNIDRYRLDKY
LLLIRRVLFSQLKYLQSRNKLVDEYIKKVLRWLPVYTGIPIHIVDILLDE
WERLLKKEEEMRKIAESAKKTPLADVIAIFQDIVADYNNSKVLREKIKED
LF
Ligand information
>5z3g Chain A (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaau
aagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaa
gcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguugua
auuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaac
aggacgucauagagggugagaaucccguguggcgaggagugcgguucuuu
guaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugg
guggccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguac
agugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgug
aaauuguugaaagggaagggcauuugaucagacaugguguuuugugcccu
cugcuccuuguggguaggggacgcauuucacugggccagcaucaguuuug
guggcaggauaaauccauaggaauguagcuugccucgguaaguauuauag
ccugugggaauacugccagcugggacugaggacugcgacguaagucaagg
augcuggcauaaugguuauaugccgcccgucuugaaacacggaccaagga
gucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaagguu
ggggccucgcaagaggugcacaaucgaccgauccggauuugaguaagagc
auagcuguugggacccgaaagauggugaccaucuaguagcugguuccugc
cgaaguuucccucaggauagcagaagcucguaucaguuuuaugguaagga
augaagagcuuuuagugggccauuuuuggagaacuggcgaugcgggauga
accgaacguagaguuaaggugccggaauacacgcucacaaaagguguuag
uucaucugaacuagcccugggcgcucaagcguguuaccuauacucuaccg
ucaggguugauaugaugcccugacgaguaggcaggcguggaggucaguga
cgaagccuagaccguaaggucgggucgaacggccucuagugcagaucuug
gugguaguagcuagaucuagcgaaaccacagccaaggcuuggguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcauugccgcgaagcuaccauccgcuggau
uauggcugaacgccucuaagucagaauccaugcuagaacgcggugaugcu
ccacacaaagauggauacgaauaaggcguccuuguggcgucgcugaacca
uagcaggcuagcaacggugcacuuggcggaaaggccuugggugcuugcug
gcgaauugcaaugucagcguggggauaaaucauuuguauacgacuuagau
guacaacgggguauuguaagcgcugagauuaagccuuuguugucugauuu
g
..........................<<<<<<.....<......>.....
.>>>>>.>.........<<....>>..<<<<<......<<.....>>...
..>>>>>..<<<..<........<<.<<<<<<...>>>>>>.>>......
..>....<<<<<<.<<<<<<<<<<<<<<<<<<<<<.....<<<<......
>>>>.(.......<<<......)>>>....>>>>>>>>..>>>>>>>>..
..>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<
<<<..>>>>>..>>>..................................<
<....>>...............<<<......>>>................
..................<<<<<.<<<<<<.....<<<<...<<<..<<<
<<<<<.......>>>>>>>>..>>>...>>>>..<<<<<<<.<<<<<<<<
<<<<<<<.....<<<<<<<<<......<<<<<<....>>>>>>.......
>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>>>....
.>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<<<<<..
...<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>....<<<<
<..<<<<<....>>>>>...>>>>>.<<....<..>......>>....>>
>>>>.>>>>>...<<.<...<<<<<<.>>>>>>......>.>>..<<<<<
<......<<<....>>>..<<<<<<<<.....<<<.<<<<<<.>>>>..>
>>>>...>>>>>>.>>..<<<<.<<<....>>>.>>>>....<<<.....
.>>>...<<<<<<<..<<<<(((.....<<<<<<.......<<<.<<<<<
<<<<..>>>>>>>>>>>>.)))......>>>>>>.>>>>..>>>>>>><<
<<<<<<<.........>>>>>>>>>....>>>>>><<<<<<<<<<.<<..
....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>.>>.....>>>>
>><<.....<<<<<..>>>>>....>>....<<<<<.>>>>>.<<<<<<<
..<<<<...<<<<<<...............>>>>>>..<<<<<...<<<<
....<<<<<<<<<......>>>>..>>>>>...>>>>..>>>>>.<<<<.
..<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>..<<
<<<<........<<..........<<<<<<.....>>>>>>......>>.
......<<<<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>
>>................>>>>>>.<<<<<<.<..<.......>..>...
..<<<<<.<<<.<<.....<..>....>>....>>>..>>>>>..>>>>>
>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5z3g Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		R15 D57 R58 R60 P61 Y228
Binding residue
(residue number reindexed from 1)		R13 D49 R50 R52 P53 Y187
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0030688 preribosome, small subunit precursor

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5z3g, PDBe:5z3g, PDBj:5z3g
PDBsum5z3g
PubMed29557065
UniProtP35178|RRP1_YEAST Ribosomal RNA-processing protein 1 (Gene Name=RRP1)

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