Structure of PDB 5dbe Chain X Binding Site BS01

Receptor Information

>5dbe Chain X (length=306) Species: 71421 (Haemophilus influenzae Rd KW20)

MAIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMV
WQAEKDGTLTKGKEIVDATNTGIALAYVAAARGYKITLTMPETMSLERKR
LLCGLGVNLVLTEGAKGMKGAIKAEEIVDPSRYVMLKQFENPANPQIHRE
TTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVAVEPV
ESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDSDTAL
ATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSASERY
LSTALF

Ligand information

>5dbe Chain A (length=6) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2)

FEYGDG

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5dbe Crystal Structure Of O-Acetylserine Sulfhydrylase From Haemophilus Influenzae In Complex With Pre-Reactive O-Acetyl Serine, Alpha-Aminoacrylate Reactionintermediate And Peptide Inhibitor At The Resolution Of 2.25A
• Resolution: 2.25 Å
• Binding residue (original residue number in PDB): G116 A117 K118 G119 M120 K121 P223 H224 K225 A231
• Binding residue (residue number reindexed from 1): G114 A115 K116 G117 M118 K119 P218 H219 K220 A226

Enzymatic activity

• Enzyme Commision number: 2.5.1.47: cysteine synthase.

Gene Ontology

Molecular Function

• GO:0004124 cysteine synthase activity
• GO:0016740 transferase activity
• GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
• GO:0080146 L-cysteine desulfhydrase activity

Biological Process

• GO:0006535 cysteine biosynthetic process from serine
• GO:0019344 cysteine biosynthetic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:5dbe, PDBe:5dbe, PDBj:5dbe
• PDBsum: 5dbe
• UniProt: P45040|CYSK_HAEIN Cysteine synthase (Gene Name=cysK)