Structure of PDB 4zo1 Chain X Binding Site BS01

Receptor Information
>4zo1 Chain X (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAVDLEAF
SHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAV
RYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTE
VALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWP
KLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
Ligand information
Receptor-Ligand Complex Structure
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PDB4zo1 Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.
Resolution3.221 Å
Binding residue
(original residue number in PDB)		K288 Q301 I302 E457
Binding residue
(residue number reindexed from 1)		K69 Q82 I83 E238
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4zo1, PDBe:4zo1, PDBj:4zo1
PDBsum4zo1
PubMed26289479
UniProtP10828|THB_HUMAN Thyroid hormone receptor beta (Gene Name=THRB)

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