Structure of PDB 4ore Chain X Binding Site BS01

Receptor Information
>4ore Chain X (length=308) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVW
QAEKDGTLTKGKEIVDATGNTGIALAYVAAARGYKITLTMPETMSLERKR
LLCGLGVNLVLTEAKGMKGAIAKAEEIVASDPSRYVMLKQFENPANPQIH
RETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVAVE
PVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDSDT
ALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSASE
RYLSTALF
Ligand information
Receptor-Ligand Complex Structure
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PDB4ore Cyrstal structure of O-acetylserine sulfhydrylase ternary complex from Haemophilus influenzae at 2.2 A
Resolution2.2 Å
Binding residue
(original residue number in PDB)		X42 T69 G71 T73 P93 M120 F144 G222 P223 H224 G228 A231
Binding residue
(residue number reindexed from 1)		X41 T68 G69 T71 P91 M117 F141 G219 P220 H221 G225 A228
Enzymatic activity
Enzyme Commision number 2.5.1.47: cysteine synthase.
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:4ore, PDBe:4ore, PDBj:4ore
PDBsum4ore
PubMed
UniProtP45040|CYSK_HAEIN Cysteine synthase (Gene Name=cysK)

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