Structure of PDB 3q0f Chain X Binding Site BS01
Receptor Information
>3q0f Chain X (length=145) Species:
3702
(Arabidopsis thaliana) [
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QIIGTVPGVEVGDEFQYRMELNLLGIHRPSQSGIDYMKDDGGELVATSIV
SSGGYNDVLDNSDVLIYTGQGGNPPKDQQLVTGNLALKNSINKKNPVRVI
RGIKKNYVYDGLYLVEEYWEETGSHGKLVFKFKLRRIPGQPELPW
Ligand information
>3q0f Chain C (length=10) [
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tactcctcag
Receptor-Ligand Complex Structure
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PDB
3q0f
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Resolution
2.75 Å
Binding residue
(original residue number in PDB)
Y378 R379 Q392 S393 G394 S412 S413 G414 Y416 D418 Y428 T429 Q431 Y486
Binding residue
(residue number reindexed from 1)
Y17 R18 Q31 S32 G33 S51 S52 G53 Y55 D57 Y67 T68 Q70 Y107
Binding affinity
PDBbind-CN
: Kd=8.7uM
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.1.1.367
: [histone H3]-lysine(9) N-methyltransferase.
External links
PDB
RCSB:3q0f
,
PDBe:3q0f
,
PDBj:3q0f
PDBsum
3q0f
PubMed
21245167
UniProt
O82175
|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5 (Gene Name=SUVH5)
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