Structure of PDB 3iqh Chain X Binding Site BS01

Receptor Information
>3iqh Chain X (length=310) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVW
QAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERK
RLLCGLGVNLVLTEGAKGMKGAIAKAEEIVASDPSRYVMLKQFENPANPQ
IHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVA
VEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDS
DTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSA
SERYLSTALF
Ligand information
Receptor-Ligand Complex Structure
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PDB3iqh Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature.
Resolution1.9 Å
Binding residue
(original residue number in PDB)
T69 T73 M120 Q143 F144 G177 G228 A231
Binding residue
(residue number reindexed from 1)
T68 T72 M119 Q142 F143 G176 G227 A230
Enzymatic activity
Enzyme Commision number 2.5.1.47: cysteine synthase.
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3iqh, PDBe:3iqh, PDBj:3iqh
PDBsum3iqh
PubMed19928859
UniProtP45040|CYSK_HAEIN Cysteine synthase (Gene Name=cysK)

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