Structure of PDB 3iqg Chain X Binding Site BS01

Receptor Information
>3iqg Chain X (length=310) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVW
QAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERK
RLLCGLGVNLVLTEGAKGMKGAIAKAEEIVASDPSRYVMLKQFENPANPQ
IHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVA
VEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDS
DTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSA
SERYLSTALF
Ligand information
Receptor-Ligand Complex Structure
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PDB3iqg Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		X42 T69 S70 G71 N72 T73 M120 Q143 G177 G228 A231 F233
Binding residue
(residue number reindexed from 1)		X41 T68 S69 G70 N71 T72 M119 Q142 G176 G227 A230 F232
Enzymatic activity
Enzyme Commision number 2.5.1.47: cysteine synthase.
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3iqg, PDBe:3iqg, PDBj:3iqg
PDBsum3iqg
PubMed19928859
UniProtP45040|CYSK_HAEIN Cysteine synthase (Gene Name=cysK)

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