Structure of PDB 3gx4 Chain X Binding Site BS01

Receptor Information
>3gx4 Chain X (length=108) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRMDEFYTKVYDAVCEIPYGKVSTYGEIARYVGMPSYARQVGQAMKHLHP
ETHVPWHRVINSRGTISKRDISAGEQRQKDRLEEEGVEIYQTSLGEYKLN
LPEYMWKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3gx4 Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y25 G26 R39 M45 K46 W56 S62 S67 R69 D70
Binding residue
(residue number reindexed from 1)		Y25 G26 R39 M45 K46 W56 S62 S67 R69 D70
Binding affinityPDBbind-CN: Kd=0.35nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003824 catalytic activity
GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0032132 O6-alkylguanine-DNA binding
Biological Process
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0070911 global genome nucleotide-excision repair
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3gx4, PDBe:3gx4, PDBj:3gx4
PDBsum3gx4
PubMed19516334
UniProtQ9UTN9|ATL1_SCHPO Alkyltransferase-like protein 1 (Gene Name=atl1)

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