Structure of PDB 3gis Chain X Binding Site BS01

Receptor Information
>3gis Chain X (length=113) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQLFCNQTACPAD
CDPNASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGP
DSALAGQIGTDCD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3gis Chain X Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3gis Molecular basis of thrombomodulin activation of slow thrombin
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D423 I424 E426 N439 L440 T443
Binding residue
(residue number reindexed from 1)		D73 I74 E76 N89 L90 T93
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005509 calcium ion binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3gis, PDBe:3gis, PDBj:3gis
PDBsum3gis
PubMed19656282
UniProtP07204|TRBM_HUMAN Thrombomodulin (Gene Name=THBD)

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