Structure of PDB 2rb1 Chain X Binding Site BS01

Receptor Information
>2rb1 Chain X (length=162) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAAAI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYK
Ligand information
Ligand ID261
InChIInChI=1S/C8H10O2/c1-2-10-8-6-4-3-5-7(8)9/h3-6,9H,2H2,1H3
InChIKeyMOEFFSWKSMRFRQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCOc1ccccc1O
ACDLabs 10.04O(c1ccccc1O)CC
FormulaC8 H10 O2
Name2-ethoxyphenol
ChEMBLCHEMBL225436
DrugBank
ZINCZINC000000404747
PDB chain2rb1 Chain X Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2rb1 Rescoring docking hit lists for model cavity sites: predictions and experimental testing
Resolution1.7 Å
Binding residue
(original residue number in PDB)		A99 M102 L118
Binding residue
(residue number reindexed from 1)		A99 M102 L118
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2rb1, PDBe:2rb1, PDBj:2rb1
PDBsum2rb1
PubMed18280498
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E)

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