Structure of PDB 2doh Chain X Binding Site BS01

Receptor Information
>2doh Chain X (length=165) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEE
NYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISK
TMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTD
PNKRWELCDIPRCTT
Ligand information
>2doh Chain C (length=24) Species: 1314 (Streptococcus pyogenes) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LTADAELQRLKNERHEEAELERLS
Receptor-Ligand Complex Structure
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PDB2doh X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y200 F205 D219 R220 E221 W225 W235
Binding residue
(residue number reindexed from 1)		Y120 F125 D139 R140 E141 W145 W155
Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
External links
PDB RCSB:2doh, PDBe:2doh, PDBj:2doh
PDBsum2doh
PubMed16964966
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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