Structure of PDB 1sgf Chain X Binding Site BS01

Receptor Information
>1sgf Chain X (length=202) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKDDQHRLV
SKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLP
TEEPKLGSTCLASGTCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSY
TCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM
AN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1sgf Chain X Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1sgf Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		D77 H82
Binding residue
(residue number reindexed from 1)		D44 H47
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H193 S195 G196
Catalytic site (residue number reindexed from 1) H154 S156 G157
Enzyme Commision number 3.4.21.35: tissue kallikrein.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1sgf, PDBe:1sgf, PDBj:1sgf
PDBsum1sgf
PubMed9351801
UniProtP00757|K1KB4_MOUSE Kallikrein 1-related peptidase-like b4 (Gene Name=Klk1b4)

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