Structure of PDB 1ofc Chain X Binding Site BS01

Receptor Information
>1ofc Chain X (length=266) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVDAYFREALKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKV
PKNTKVQREEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKA
NEKYGRDDIDNIAKDVEGKTPEEVIEYNAVFWERCTELQDIERIMGQIER
GEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYGNNKGKNYTEIEDRFLV
CMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLIT
LIERENIELEEKERAE
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain1ofc Chain X Residue 1978 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1ofc Crystal Structure and Functional Analysis of a Nucleosome Recognition Module of the Remodeling Factor Iswi
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E828 G829 K830 A976 E977
Binding residue
(residue number reindexed from 1)		E117 G118 K119 A265 E266
Annotation score4
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0031491 nucleosome binding
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1ofc, PDBe:1ofc, PDBj:1ofc
PDBsum1ofc
PubMed14536084
UniProtQ24368|ISWI_DROME Chromatin-remodeling complex ATPase chain Iswi (Gene Name=Iswi)

[Back to BioLiP]