Structure of PDB 6woo Chain WW Binding Site BS01

Receptor Information
>6woo Chain WW (length=129) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGY
VILTTSAGIMDHEEARRKHVSGKILGFVY
Ligand information
>6woo Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguug
gccggucgauuuuccaacggggccuuuccuucuggcuaaccuugaguccu
uguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcguauugcucgaauauauuagcauggaauaauagaauaggac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuu
aaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugaccc
acucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaug
gucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagu
ggagccugcggcuuaauuugacucaacacggggaaacucaccagguccag
acacaauaaggauugacagauugagagcucuuucuugauuuugugggugg
uggugcauggccguucuuaguugguggagugauuugucugcuuaauugcg
auaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugg
uuauccacuucuuagagggacuaucgguuucaagccgauggaaguuugag
gcaauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcu
acacugacggagccagcgagucuaaccuuggccgagaggucuugguaauc
uugugaaacuccgucgugcuggggauagagcauuguaauuauugcucuuc
aacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguc
ccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuag
ugaggccucaggaucugcuuagagaagggggcaacuccaucucagagcgg
agaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagg
uuuccguaggugaaccugcggaaggaucau
..<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<..<<..<<....<<<................<<......<<.
<<<.....>>>.>>......>>........<<<<<............>>>
>><...<<<<<<......((((((..<<<....>>>....<<......>>
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<..<......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>
>>>.........<<<[[.....<.<<...<<<........<<<<<.<<<<
.....<..>.....>>>>.>>>>>......<<<<.....<<....<<...
....>>....>>.....>>>>....<<<<<.<<.......<<...<....
...>..<<<.....>>>....>>......>>.>>..>>>.........<<
<..<<<<<<<<......)))))).>>>>>>>>.>>>...........<<<
<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.
>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>
...>>.>....<<<<<.....<...<<<<.<.....>.>>>>...>..>>
>>>..........<<<.<<..<<..<<<<<<<<.<<<........>>>>>
>>>>>>..>>....<<..]]>>...>>.....>>>.>>>.<<<......<
<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<
..<<<.<<<<<<......<<........>>..........<<<<<.....
.<<<<<........<<.<<<........>>>.>>......>>>>>...<<
.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<......>>>
...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>
>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>
>....>>>.>>>...>.>>>>>>>.......>>>>>...>>.>>>>.>>>
.....<<<<<<<......<<.....<<..<<<<....>>>>..>>....>
>.......>>>>>>>...........<<<<<<..........>>>>>>..
........>>>>>>....<<<<<<<<.......>>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<
<..<.<<..<...<<<<<............................>>>>
>...>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>....
.<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6woo An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T2 R3 S4 V6 A8 N12 N16 K19 K22 R28 S31 K32 R57 K60 K71 V74 I75 S76 R78 N80 V81 K82 I83 K88 T105 T106 S107 E115 R118 K119 H120 S122 K124 Y130
Binding residue
(residue number reindexed from 1)		T1 R2 S3 V5 A7 N11 N15 K18 K21 R27 S30 K31 R56 K59 K70 V73 I74 S75 R77 N79 V80 K81 I82 K87 T104 T105 S106 E114 R117 K118 H119 S121 K123 Y129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6woo, PDBe:6woo, PDBj:6woo
PDBsum6woo
PubMed
UniProtP0C0W1|RS22A_YEAST Small ribosomal subunit protein uS8A (Gene Name=RPS22A)

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