Structure of PDB 3jag Chain WW Binding Site BS01

Receptor Information
>3jag Chain WW (length=129) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFE
IIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGF
IVLTTSAGIMDHEEARRKHTGGKILGFFF
Ligand information
>3jag Chain 9 (length=1719) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgccacuuggauaacugugguaauuc
uagagcuaauacaugccgacgggcgcugacccccuucgcgggggggaugc
gugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgccc
cccguggcggcgacgaccauucgaacgucugcccuaucaacuuucgaugg
uagucgccgugccuaccauggugaccacgggugacggggaaucaggguuc
gauuccggagagggagccugagaaacggcuaccacauccaaggaaggcag
caggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaau
aacaauacaggacucuuucgaggcccuguaauuggaaugaguccacuuua
aauccuuuaacgaggauccauuggagggcaagucuggugccagcagccgc
gguaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagc
ucguaguuggaucuugggagcgggcguccccgccgccucucggccggggc
ccgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcccgagcc
gccuggauaccgcagcuaggaauaauggaauaggaccgcgguucuauuuu
guugguuuucggaacugaggccaugauuaagagggacggccgggggcauu
cguauugcgccgcuagaggugaaauucuuggaccggcgcaagacggacca
gagcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaagucg
gagguucgaagacgaucagauaccgucguaguuccgaccauaaacgaugc
cgaccggcgaugcggcggcguuauucccaugacccgccgggcagcuuccg
ggaaaccaaagucuuuggguuccggggggaguaugguugcaaagcugaaa
cuuaaaggaauugacggaagggcaccaccaggaguggagccugcggcuua
auuugacucaacacgggaaaccucacccggcccggacacggacaggauug
acagauugauagcucuuucucgauuccgugggugguggugcauggccguu
cuuaguugguggagcgauuugucugguuaauuccgauaacgaacgagacu
cuggcaugcuaacuaguuacgcgacccccgagcggucggcgucccccaac
uucuuagagggacaaguggcguucagccacccgagauugagcaauaacag
gucugugaugcccuuagauguccggggcugcacgcgcgcuacacugacug
gcucagcgugugccuacccuacgccggcaggcgcggguaacccguugaac
cccauucgugauggggaucggggauugcaauuauuccccaugaacgagga
auucccaguaagugcgggucauaagcuugcguugauuaagucccugcccu
uuguacacaccgcccgucgcuacuaccgauuggaugguuuagugaggccc
ucggaucggccccgccggggugcccuggcggagcgcugagaagacggucg
aacuugacuaucuagaggaaguaaaagucguaacaagguuuccguaggug
aaccugcggaaggaucauu
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<...<<<..........>>>..>>.>>......<<...
.....<<<.<....<<....<<<<.......<<.....<<.<<<.....>
>>.>>......>>.........<<<<...<<<<<<....>>>>>>...>>
>>....<<<<<...<......>..>>>>>...........<<<<.<<<<.
.....>>>>>>>>..>>>>...>>..>.>>>.<<<....<<<....<<<<
<<<.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>
....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>
>>>>>.........<<<....<<<<...>>>>..>>>..>...>>.>...
..<<.<<<<<<.<<<....>>>..>>>>>>..>>......<<..<.....
......>..>>.........<<<<<((......<<<<.....<<..))>>
.......>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.
<<...<<<.<<.....<<.<.<<....>>.>.>>.<.<..<<........
>.>>.>...<<<<<<.<.......<<...<.......>.<<<<.......
>>>>...>>......>.>>>..>>>.......<<....<<<<<<<.....
..........>>>>>>>...>>....>>....<<<<<<..<...<<<<..
<<<.<<<<<<<<...<<<......>>>......>>>>>>>>.>>>.....
..<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<<
<<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<<
<.<<.<<<..<.<<<<<<.<<<........>>>>>>>>>.>..>>>...<
<.)).>>...>>.....>>>.>.>.<<<......<<<<....>>>>....
>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<...
...<<........>>..........<<<<<.<....<<<<<.........
<..<<........>>..>.......>>>>>...<<.<<<..<<.<<<<<<
....<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<
<...<...<<<<..<<<.....<<<...<<<....>>>..>>>.....>>
>..>>>>..>.....<<<<<.....>>>>>........>>>....>>>.>
>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<.<<
<........<.......<<<.<<<<....>>>>.>>>....>........
.>>>.>>......<.....<<<<<..........>>>>>.....>.....
>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.
<<...<<<<<.<<<<<<<<<..>>>>>>>>>...>>>>>...>>.>>>>.
.>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<.
.>>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jag Structural basis for stop codon recognition in eukaryotes.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		V2 R3 M4 V6 D9 K12 S13 N16 K19 R20 K22 R28 S31 K32 R57 K60 K71 V74 I75 S76 R78 Q82 K88 W89 T105 T106 S107 H120 G122 K124 F130
Binding residue
(residue number reindexed from 1)		V1 R2 M3 V5 D8 K11 S12 N15 K18 R19 K21 R27 S30 K31 R56 K59 K70 V73 I74 S75 R77 Q81 K87 W88 T104 T105 S106 H119 G121 K123 F129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jag, PDBe:3jag, PDBj:3jag
PDBsum3jag
PubMed26245381
UniProtG1TG89|RS15A_RABIT Small ribosomal subunit protein uS8 (Gene Name=RPS15A)

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