Structure of PDB 8s8i Chain W Binding Site BS01

Receptor Information
>8s8i Chain W (length=129) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIADVEKWTANLLPARQFGY
VILTTSAGIMDHEEAHRKHVSGKILGFVY
Ligand information
>8s8i Chain 2 (length=1789) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccgguccgcgcgcacugguuuucaaccggaucuuuccuucuggcuaacc
uguacuccuugugggugcaggcgaaccaggacuuuuacuuugaaaaaauu
agaguguucaaagcaggcgaaagcucgaauauauuagcauggaauaaugg
aauaggacguuugguucuauuuuguugguuucuaggaccaucguaaugau
uaauagggacggucgggggcaucaguauucaauugucagaggugaaauuc
uuggauuuauugaagacuaacuacugcgaaagcauuugccaaggacguuu
ucauuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccguc
guagucuuaaccauaaacuaugccgacuagggaucgggugguguuuuucu
uaugacccacucggcaccuuacgagaaaucaaagucuuuggguucugggg
ggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacca
ccaggaguggagccugcggcuuaauuugacucaacacggggaaacucacc
agguccagacacaauaaggauugacagauugagagcucuuucuugauuuu
gugggugguggugcauggccguucuuaguugguggagugauuugucugcu
uaauugcgauaacgaacgagaccuuaaccuacuaaauaggguugcuggca
cuugccgguugacucuucuuagagggacuaucgguuucaagccgauggaa
guuugaggcaauaacaggucugugaugcccuuagacguucugggccgcac
gcgcgcuacacugacggagccagcgaguacaaccuuggccgagaggucug
gguaaucuugugaaacuccgucgugcuggggauagagcauuguaauuauu
gcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguuga
uuacgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaau
ggcuuagugaggccucaggauuugcuuagagaagggggcaacuccaucuc
agagcgaagaaucuggucaaacuuggucauuuagaggaacuaaaagucgu
aacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[................<<.....<<.
<<<.....>>>.>>......>>........<<<<<..<<....>>..>>>
>>[...((((((......<<<<<<<.<<<....>>>..............
)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}}
}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<........
..>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<.
....>>>..>>>...............<<.<<<<<<.<.......>..>>
>>>>..>>......<<..<...........>..>>.........<<<<<(
(....<.<<<<.....<<..))>>.......>>>>>>>>>>..))))))]
]]].........[[[<<.......{{...[[[.{{....<<<<<<<<<<<
.<<<<..<..>....>>>>....>>>>>>>>>>>....<<<<<<......
<<.<<<.......>>>.>>......>>>>>>...<<<<<.<<.......<
<...<.......>..<<<....>>>....>>......>>.>>..>>>...
......[[[..(((((((......>>>>>>>..))))))).]]].....}
}....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<......>>>
......>.>>>>>>.>>>.......<<....>>...>>>>..>.>>>>.>
>>...]]]...}}......<<<<<<<...<...<<<<.<.....>.>>>>
...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<.<<<.....
...>>>>>>>>>>>..>>>...<<..>>>>...>>.....>>>.]]].<<
<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<..<
<.<<<<<<..<<<.<<<<<<......<<........>>..........<<
<<<.<....<<<<<........<<.<<<........>>>.>>......>>
>>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<.
.....>>>...>>.>>>....<<<<<.<<..<<<<..<<<<<<<<<<<<.
...>>>>>>.>>>>>>..>>>>.>>....<<<<<<.....>>>>>>....
...>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>>.>
>>>.>>>.....<<<<<<<......<<.....<<<.<<<<....>>>>.>
>>....>>.......>>>>>>>......<....<<<<<<..........>
>>>>>....>.....>>>>>>....<<<<<<<<.......>>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<
<<<<.<<<..<<<<..<...<<<<<<........................
..>>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>.
..>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8s8i Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution4.3 Å
Binding residue
(original residue number in PDB)
T2 R3 T4 V6 A8 D9 N12 N16 R28 S31 K32 R57 K60 K71 V74 I75 S76 R78 N80 K82 I83 T105 T106 S107 R118 K119 H120 S122 Y130
Binding residue
(residue number reindexed from 1)
T1 R2 T3 V5 A7 D8 N11 N15 R27 S30 K31 R56 K59 K70 V73 I74 S75 R77 N79 K81 I82 T104 T105 S106 R117 K118 H119 S121 Y129
External links
PDB RCSB:8s8i, PDBe:8s8i, PDBj:8s8i
PDBsum8s8i
PubMed39193907
UniProtQ6CW21|RS22_KLULA Small ribosomal subunit protein uS8 (Gene Name=RPS22)

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