BioLiP

Receptor Information

>8ea4 Chain W (length=514) Species: 34078 (Scytonema hofmannii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LEKNVIATQLSEEAQVKLEVIQSLLEPCDRTTYGQKLREAAEKLNVSLRT
VQRLVKNWEQDGLVGLTQTSRADKGKHRIGEFWENFITKTYKEGNKGSKR
MTPKQVALRVEAKARELKDSKPPNYKTVLRVLAPILEKQQKAKSIRSPGW
RGTTLSVKTREGKDLSVDYSNHVWQCDHTRVDVLLVDQHGEILSRPWLTT
VIDTYSRCIMGINLGFDAPSSGVVALALRHAILPKRYGSEYKLHCEWGTY
GKPEHFYTDGGKDFRSNHLSQIGAQLGFVCHLRDRPSEGGVVERPFKTLN
DQLFSTLPGYTGSNVQERPEDAEKDARLTLRELEQLLVRYIVDRYNQSID
ARMGDQTRFERWEAGLPTVPVPIPERDLDICLMKQSRRTVQRGGCLQFQN
LMYRGEYLAGYAGETVNLRFDPRDITTILVYRQENNQEVFLTRAHAQGLE
TEQLALDEAEAASRRLRTAGKTISNQSLLQEVVDRDALVATKKSRKERQK
LEQTVLRSAAVDES

>8ea4 Chain 1 (length=98) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccgacgacagataatttgtcactgtacagtagaatatagatgcgcatcta
tatagatgcaaattgagtggccttattaaatgacttctcaaccagtca

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8ea4 Structures of the holo CRISPR RNA-guided transposon integration complex.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	R58 R77 K84 R99 D101 K102 G103 K104 H105 R106 I107 N152 K154 T155 R158 A246 K290 N295 R420
Binding residue (residue number reindexed from 1)	R30 R49 K56 R71 D73 K74 G75 K76 H77 R78 I79 N124 K126 T127 R130 A218 K262 N267 R392

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding

	Biological Process
GO:0015074	DNA integration

PDB	RCSB:8ea4, PDBe:8ea4, PDBj:8ea4
PDBsum	8ea4
PubMed	36442503
UniProt	A0A979HMQ2

[Back to BioLiP]

Structure of PDB 8ea4 Chain W Binding Site BS01