Structure of PDB 8cq7 Chain W Binding Site BS01

Receptor Information
>8cq7 Chain W (length=102) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQIHKIRITLTSTKVKQLENVSANIIRNAAQYNIVKKGPVRMPTKVLKIT
TRKTPNGEGSKTWDAYEMRIHKRVIDLQAPASTVKRITQITIEPGVDVEV
TI
Ligand information
>8cq7 Chain B (length=1756) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguaccuuacuacuuggauaaccgu
gguaauucuagagcuaauacaugcuuaaaaucccgacuguuuggaaggga
uguauuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucau
aauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaau
uucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuca
acggguaacggggaauaaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccga
cacggggagguagugacaauaaauaacgauacagggcccuuuugggucuu
guaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagg
gcaagucuggugccagcagccgcgguaauuccagcuccaaaagcguauau
uaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcugg
ccgguccgcguacuggacccagccgagccuuuccuucuggguagccauuu
auggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuaugguu
cuauuuuguugguuucuaggaccaucguaaugauuaauagggacggucgg
ggguaucaguauucaguugucagaggugaaauucuuggauuuacugaaga
cuaacuacugcgaaagcauuuaccaaggacguuuucauuaaucaagaacg
aaaguuaggggaucgaagaugaucagauaccgucguagucuuaaccauaa
acuaugccgacuagggaucgguuguuguucuuuuauugacgcaaucggca
ccuuacgagaaaucaaagucuuuggguucuggggggaguauggucgcaag
gcugaaacuuaaaggaauugacggaagggcaccaccaggaguggagccug
cggcuuaauuugacucaacacggggaaacucaccagguccagacacaaua
aggauugacagauugagagcucuuucuugauuuugugggugguggugcau
ggccguucuuaguugguggagugauuugucugcuuaauugcgauaacgaa
cgagaccuuaaccuacuaaauagugcugcuagcauuugcugguauaguca
cuucuuagagggacuaucgauuucaagucgauggaaguuugaggcaauaa
caggucugugaugcccuuagacguucugggccgcacgcgcgcuacacuga
cggagccagcgaguauaagccuuggccgagaggucugggaaaucuuguga
aacuccgucgugcuggggauagagcauuguaauuguugcucuucaacgag
gaauuccuaguaagcgcaagucaucagcuugcguugauuacgucccugcc
cuuuguacacaccgcccgucgcuacuaccgauugaauggcuuagugaggc
cuccggauugguuuauucuggaaccgagaagcuggucaaacuuggucauu
uagaggaaguaaaagucguaacaagguuuccguaggugaaccugcggaag
gaucau
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<.......>>..>......>>........<<<<<..<<....>>..>>>>
><...<<<<<<.......{.((((.<<<....>>>..............>
>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>
..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.........
.>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<.
..>>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>
>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<..
....................>>>>>>>>>>.....<<<<...........
.........>>>>....<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<<<<<<
<<......)))).}...>>>>>>>>>>>.....>>....<<<<<<.<<..
.<<<<..<<..<<<<<<.<...<<<......>>>......>.>>>>>>..
>>.......<<....>>...>>>>...>>>>>.>>>...>>>...>>.>.
...<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.....
.....<<<.<<.<<<..<<<<<<<<..<<........>>.>>>>>>>>..
>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<<<....>
>>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<
<<<<......<<........>>..........<<<<<.<....<<<<<..
......<<.<<<........>>>.>>......>>>>>...<<.<<<..<<
.<<<<<.....<<<.<<<<<....>>>...<<<......>>>...>>.>>
>....<<<<<.<<..<<<<..<<<<.<<<<<<<....>>>>>>>....>>
>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>.....>
>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<
<<<<<......<<......<<<.<<<<....>>>>.>>>....>>.....
..>>>>>>>......<....<<<<<<..........>>>>>>....>...
..>>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>
>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<
<..<...<<<<<<........>>>>>>...>..>>>>..>>>.>>>>>>>
>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.2 Å
Binding residue
(original residue number in PDB)
R22 E34 K52 G53 V55 R56 M57 P58 T65 T66 R67 K68 T69 P70 N71 G72 E73 G74 S75 K76 T77 W78 R84 H86 K87
Binding residue
(residue number reindexed from 1)
R7 E19 K37 G38 V40 R41 M42 P43 T50 T51 R52 K53 T54 P55 N56 G57 E58 G59 S60 K61 T62 W63 R69 H71 K72
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