Structure of PDB 7xse Chain W Binding Site BS01

Receptor Information
>7xse Chain W (length=533) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQRLLIPTVDDPGIWGVKVRLGKEKDVVRQILKKKLAREGTKNPLEIYSA
FQRDSFKGHVYIEARKAEAINDALKGNVNVFSNNSKFLVGIVEYKDLLRP
VKSSDVKLTRGSYVRVKNGKFKGDLAQVDEVLENGLEARLKLVPRLDYGF
RPAQRLFSEAEARVHEPTIRRDRDGFVTYGGEEYYEGFLYKTFRLQNLIV
NSINPTLNELSLFQSNEESTTIDLSTIADSLKETAKNLVSFQPGDNVEII
NGELNHLTGTVSSVNQSTIVSVRLHSDDDTINSETVEIPTSDLRKIFNVG
DHVRVIHGKHTDDTGLIVEVNGDKVEFISNQTKRTVIVFSNYLIKSTDST
VSINESGRFELHDLVQVNSDLVGIVIRAQKDSFDVLCSDGKLLSLPPVSI
YSKLNLNPNQQIAIDSNGVEVKVGDTVREFTGERRQGTILHVYRNFLFLR
SREIVENQGVFVTSSNRVKTIRDPTLNKTVKIRQGGYKGKIGIVKEANGD
RFRVELHNPNKTIPIPCSFLLIESTHGWVPYED
Ligand information
>7xse Chain T (length=134) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattacacccaagacaccaggcacgagacagaaa
Receptor-Ligand Complex Structure
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PDB7xse Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
R431 Q433
Binding residue
(residue number reindexed from 1)
R194 Q196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003711 transcription elongation factor activity
GO:0003729 mRNA binding
GO:0140463 chromatin-protein adaptor activity
Biological Process
GO:0006325 chromatin organization
GO:0006354 DNA-templated transcription elongation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0032784 regulation of DNA-templated transcription elongation
Cellular Component
GO:0005634 nucleus
GO:0032044 DSIF complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7xse, PDBe:7xse, PDBj:7xse
PDBsum7xse
PubMed35981082
UniProtC4R370

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