Structure of PDB 7q0p Chain W Binding Site BS01

Receptor Information
>7q0p Chain W (length=87) Species: 237561 (Candida albicans SC5314) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MENDKGQLVELYVPRKCSATNRIIKAKDHASVQISIAKVDEDGRAIAGEN
ITYALSGYVRGRGEADDSLNRLAQQDGLLKNVWSYSR
Ligand information
>7q0p Chain A (length=1692) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagauaaaaauuugaugauucauaauaacuuuucgaaucgcauggcc
uugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgaugg
uaggauaguggccuaccaugguuucaacggguaacggggaauaaggguuc
gauuccggagagggagccugagaaacggcuaccacauccaaggaaggcag
caggcgcgcaaauuacccaaucccgacacggggagguagugacaauaaau
aacgauacagguuguaauuggaaugaguacaauguaaauaccuuaacgag
gaacaauuggagggcaagucuggugccagcagccgcgguaauuccagcuc
caaaagcguauauuaaaguuguugcaguuaaaaagcucguaguugaaccu
ugggcuuggcuggccgguccuggacccagccgagccuuuccuucuggcca
ggacuuuuacuuugaaaaaauuagaguguucaaagcaggccuuugcucga
auauauuagcauggaauaauagaauaggacguuaugguucuauuuuguug
guuucuaggaccaucguaaugauuaauagggacggucggggguaucagua
uucaguugucagaggugaaauucuuggauuuacugaagacuaacuacugc
gaaagcauuuaccaaggacguuuucauuaaucaagaacgaaaguuagggg
aucgaagaugaucagauaccgucguagucuuaaccauaaacuaugccgac
uagggaucgguuguuguucuuuuauugacgcaaucggcaccuuacgagaa
aucaaagucuuuggguucuggggggaguauggucgcaaggcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcuuaauuu
gacucaacacggggaaacucaccagguccagacacaauaaggauugacag
auugagagcucuuucuugauuuugugggugguggugcauggccguucuua
guugguggagugauuugucugcuuaauugcgauaacgaacgagaccuuaa
ccuacuaaauagugcugcuagcauuugcugguauagucacuucuuagagg
gacuaucgauuucaagucgauggaaguuugaggcaauaacaggucuguga
ugcccuuagacguucugggccgcacgcgcgcuacacugacggagccagcg
aguauaagccuuggccgagaggucugggaaaucuugugaaacuccgucgu
gcuggggauagagcauuguaauuguugcucuucaacgaggaauuccuagu
aagcgcaagucaucagcuugcguugauuacgucccugcccuuuguacaca
ccgcccgucgcuacuaccgauugaauggcuuagugaggccuccggauugg
uuuagggaaccgagaagcuggucaaacuuggucauuuagaggaaguaaaa
gucguaacaagguuuccguaggugaaccugcggaaggaucau
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<<....
.>>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<....................>>>>>>.....>...<<<<..<<<.
....>>>.>>>>....>>>...>>>>..>>>.<<<....<<<....<<<<
<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....>>>>
....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>
>>>>>.........<<<....<<<<...>>>>..>>>..>....>.>...
..<<<<...<..>...>>>>......<<..<...........>..>>...
......<<<<<((....<.<<<<.....<<..))>>.......>>>>>>>
>>>..>>>>>>>>>>.........<<<((.....<.<<...<<<.<<...
.<<<<<<<<<<<<............>>>>>>>>>>>>....<<<<<..>>
>>>...<<<<<.<<.......<<...<.......>..<<<....>>>...
.>>......>>.>>..>>>.........<<<..<<<<<<<<<........
.....>>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..
<<<<<<.<...<<<......>>>......>.>>>>>>..>>.......<<
....>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<.
..<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<
.<<<..<<<<<<<<..<<........>>.>>>>>>>>..>>>...<<..)
)>>...>>.....>>>.>>>.<<<......<<<<....>>>>....>>>.
.)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<
<........>>..........<<<<<.<....<<<<<........<<.<<
<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<.....
<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.
<<..<<<<..<<<<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>
....<<<<<<.....>>>>>>.......>>>>>.....>>.>>>.....>
>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<<<<<<......
<<......<<<.<<<<....>>>>.>>>....>>.......>>>>>>>..
....<....<<<<<<..........>>>>>>....>.....>>>>>>...
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<..<...<<<<
<.......>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...
>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7q0p E-site drug specificity of the human pathogen Candida albicans ribosome.
Resolution2.77 Å
Binding residue
(original residue number in PDB)		Y58 R62
Binding residue
(residue number reindexed from 1)		Y58 R62
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7q0p, PDBe:7q0p, PDBj:7q0p
PDBsum7q0p
PubMed35613268
UniProtA0A1D8PCG7|RS21B_CANAL Small ribosomal subunit protein eS21 (Gene Name=RPS21B)

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