Structure of PDB 7ohy Chain W Binding Site BS01

Receptor Information
>7ohy Chain W (length=227) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSKRSAQTDKKGRENKERIFDEVREALDTYRYVWVLHLDDVRTPVLQEIR
TSWAGSKLIMGKRKVLQKALGEKREEEYKENLYQLSKLCSGVTGLLFTDE
DVNTVKEYFKSYVRSDYSRPNTKAPLTFTIPEGIVYSRGGQIPAEEDVPM
IHSLEPTMRNKFEIPTKIKAGKITIDSPYLVCTEGEKLDVRQALILKQFG
IAASEFKVKVSAYYDNDSSTVESTNIN
Ligand information
>7ohy Chain 1 (length=1689) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaauaucaauaag
cggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcg
gcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauu
uggagagggcacuuuggggccguuccuugucuauguuccuuggaacagga
cgucauagagggugagaaucccguguggcgaggagugcgguucuuuguaa
agugccuucgaagagucgaguuguuugggaaugcagcucuaagugggugg
uuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacag
ugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaa
auuguugaaagggaagggcauuugaucagacaugguguuuugugcccucu
gcuuaggggaaucucgcauuucacugggccagcaucaguuuugguggcag
gauaaauccauaggaauguagcuugccucgguaaguauuauagccugugg
gaauacugccagcugggacugaggacugcgacguaagucaaggaugcugg
cauaaugguuauaugccgcccgucuugaaacacggaccaaggagucuaac
gucuaugcgaguguuuggguguaaaacccauacgcguaauggugaacgua
gguuggggccucgcaagaggugcacaaucgaccgauccuggauggauuug
guaagagcauagcuguugggacccgaaagauggugaaaaccaucuaguac
ugguuccugccgaaguuucccucaggauagcagaagcucguaucaguuuu
auuaagaaugaagagcuuuuagugggccauuuuugguaagcagaacuggc
gaugcgggaugaaccgaacguagaguuaaggugccggaauacacgcucau
cagaccaaaagguguuaguucaucuagacagccggacgguggccauggaa
gucggaauccgcuaaggaguguguaacaacucaccggccgaaugaacuag
cccuguggcgcucaagcguguuaccuauacucuaccgucaggguugauug
augcccugacgaguaggcaggcguggaggucagugacgaagccuagaccg
uaaggucgggucgaacggccucuagugcagaucuuggugguaguagcagc
gaaaccacagccaagggacgggcuuggcagaaucagcgggcagucgcgac
auugcuauaccgaagcagaauucgguaacccuacugaugaauguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcagccgcgaagcuaccauccgcuggauua
uggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucuu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguagaguagccuuguug
uuacgaucugcugagauuaaccuuuguugucugauuugu
...........................<<<<<.....<...>......>>
>>>...........<<....>>..<<<<<......<<.....>>.....>
>>>>..<<<...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<<<<<.<<<<<<<<<<<<<<<<<.....<<<<......>>>>
.((......<<<.....))>>>....>>>>>>>>>..>>>>>>>.....>
>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<
..>>>>>>..>>>..................................<<.
...>>...............<<<......>>>..................
................<<<<<.<<<<<......<<<<...<<<<.<<<..
......>>>.....>>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<
.....<<<<<<<<<......<<<<<......>>>>>.......>>>>>>>
.>.>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>
>.....>>>>>.>>>>>..<<<<........>>>><<<<<<....<<<<<
<.<<<<<<..<<<...<<<<.....>>>>...>>>...<<.>>.......
<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<.....>>>>>.>
>>....>>>>>>.>>>>>>..<<.<...<<<<<<....>>>>>>.....>
.>>..<<<<<<......<........>..<<<<<<<<<....<<<.<<<<
<.>>>.>>>>>..>>>>>>>.>>..<<<<.<.<<<.....>>>.>.>>>>
....<<<......>>>...<<<<<<<..<<<<(((.....<<<<<<....
.<<......<<<.<<<<<<<<<<.......<<<<<.<<<...<<......
...>>...>>>.........<<......>>...>>>>>...>>>>>>>>>
>>>>..))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......
..>>>>>>>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<.
...>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.>>
....>>....<<<<<.......>>>>>....<<<<<..<<<<<.......
.>>>>>.<<<<<<<......>>>>>>>......>>>>>....<<<<<<<<
..<<<<.<.<<<<<<...............>>>>>>.><<<<<...<<<<
....<<<<<<............>>>>>>...>>>>..>>>>>.<<<<...
<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>.....
..<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<......
.......>.....<<<<<<<<<.<<<......<<................
.......>>.....>>>...>>>.>>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ohy Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R3 S4 K5 R6 S7 A13 T15 D16 K17 K18 R20 I26 D47 R49 T50 Q54 R57 M67 K69 R70 K71 K75 S160 K204 Q205
Binding residue
(residue number reindexed from 1)		R1 S2 K3 R4 S5 A6 T8 D9 K10 K11 R13 I19 D40 R42 T43 Q47 R50 M60 K62 R63 K64 K68 S153 K197 Q198
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0000055 ribosomal large subunit export from nucleus
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor
GO:0032040 small-subunit processome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ohy, PDBe:7ohy, PDBj:7ohy
PDBsum7ohy
PubMed34813592
UniProtP33201|MRT4_YEAST Ribosome assembly factor MRT4 (Gene Name=MRT4)

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