Structure of PDB 7of2 Chain W Binding Site BS01

Receptor Information
>7of2 Chain W (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNLGGKSSGRRQGIKKMEGHYVHAGNIIATQRHFRWHPGAHVGVGKNKCL
YALEEGIVRYTKEVYVPHPRNTEAVDLITRLPKGAVLYKTFVHVVPAKPE
GTFKLVAML
Ligand information
>7of2 Chain A (length=1410) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccagacaaccuuagccaaa
ccauuuacauaaaguauaggcgauagaaauugauggcgcaauagauauag
uaccgcaagggaaagaugaaaaaccaagcauaauauagcaaggacuaacc
ccuauaccuucugcauaaugaauuaacuagaaauaacuuugcaaggagag
ccaaagcuaagacccccgaaaccagacgagcuaccuaagaacagcuaaaa
gagcacacccgucuauguagcaaaauagugggaagauuuauagguagagg
cgacaaaccuaccgagccuggugauagcugguuguccaagauagaaucuu
aguucaacuuuaaauuugcccacagaacccucuaaauccccuuguaaauu
uaacuguuaguccaaagaggaacagcucuuuggacacuaggaaaaaaccu
uguagagagaguaaaaaauuuaacacccauaguaggccuaaaagcagcca
ccaauuaagaaagcguucaagcucaacacaaaaaucccaaacauauaacu
gaacuccucacacccaauuggaccaaucuaucacccuauagaagaacuaa
uguuaguauaaguaacaugaaaacauucuccuccgcauaagccugcguca
gauacugacaauuaacagcccaauaucuacaaucaaccaacaagucauua
uuacccucacugucaacccaacacaggcaugcucauaaggaaagguuaaa
aaaaguaaaaggaacucggcaaaucuuaccccgccuguuuaccaaaaaca
ucaccucuagcaucaccaguauuagaggcaccgccucacuuguuccuuaa
auagggaccuguauggcuccacgaggguucagcugucucuuacuuuuaac
cagugaaauugaccugcccgugaagaggcgggcauaacacagcaagacga
gaagacccuauggagcuuuaauuuauuaaugcaaacaccugcauuaaaaa
uuucgguuggggcgaccucggagcagaacccaaccuccgagcaguacaug
cuaagacuucaccagucaaagcgaaccucaauugauccaauaacuugacc
aacggaacaaguuacccuagggauaacagcgcaauccuauucuagagucc
auaucaacaauaggguuuacgaccucgauguuggaucaggacaucccgau
ggugcagccgcuauuaaagguucguuuguucaacgauuaaaguccuacgu
gaucugaguucagaccggaguaauccaggucgguuucuaucuacuuuaau
uccucccuguacgaaaggacaagagaaauaaggccuacuucacaaagcgc
cuucccccguaaaugauaucaucucaacuuaguauuauacccacacccaa
gaacaggguu
<<<.......<<<<.................................<..
....>...........<<.....>>.........>>.>>...........
..<<....>>................>>>...........<<<.......
>>>...<.<........>.>.<<<<<<.........<<<.<<..<<....
>>...>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<....
.>>>...<<<<.<<<<........>>>>>>>>....>>>.>>>>>...<<
.......>>......>.>>>>......>.>>..<<<<<<....<<<<...
.>>>><<<.<<<<<<<<<<.....<<..........>>.....>>>>>>>
>>>..>>>.<<<<<<<<<<......>>>>>>>>>>.<.<<<......>>>
.>..<<<.<<<...<..............<....<<<.........>>>.
...>.......<<<......>>>..........................>
...>>>>>>........>>>>>>...<<<<<......>>>>>........
.>>>>>><......<<..<<<....>>><<<<..<<<<........<<<<
<...>>>>>......<<<...<<<<.......................>>
>>.......>>>.....<<......>>.>>>>.....>>>>..<<<<...
<<<<<<<<.<<................<<<<<<..<<<.........>>>
...<<<<<<.............>>>>>>....<<<..<<..<<<<<<...
..>>>>>>..>>..>>>....>>.>>>>........>>.>>>>>>>>>>>
>.>>.....>.....<<<<<........>>>>>.......<<..<<<.<<
......<<<<.<<<<<<..<<<<<.<<<<<<<<......>>>>>>>>>>>
>>..<<<<.....>>>><<<<<<...........>>>>>>..<<.....<
<<..<<<<.....>>>>..>>>....>>.........<<<....>>>...
.........>>>>..>>>>>>.......<<<....<<<<<<...<<....
...>>...>>>>>>.....>>.>.......<<<<<..<<<<<..<<.<<<
<<<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>....
..>>>>.>....<<<<<<<....>>>.>>>>....>>..>>>.>>...<<
<.<<<.................>>>.>>><<<<<...<<<....>>>.>>
>>>......<<<................>>>.............<<<<..
.....>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of2 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		N41 L42 G43 G44 K45 S46 S47 G48 R49 R50 Q51 I53 K54 M56 E57 H59 A63 G64 N65 I66 R71 R74 W75 G84 K85 N86 C88 Y90 Y99 K101 T129
Binding residue
(residue number reindexed from 1)		N2 L3 G4 G5 K6 S7 S8 G9 R10 R11 Q12 I14 K15 M17 E18 H20 A24 G25 N26 I27 R32 R35 W36 G45 K46 N47 C49 Y51 Y60 K62 T90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of2, PDBe:7of2, PDBj:7of2
PDBsum7of2
PubMed34135319
UniProtQ9P0M9|RM27_HUMAN Large ribosomal subunit protein bL27m (Gene Name=MRPL27)

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