Structure of PDB 7aqs Chain W Binding Site BS01

Receptor Information
>7aqs Chain W (length=156) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNLLYTRNDVSDSEKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIA
VHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDI
HNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLWF
IESNIE
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7aqs Chain U Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7aqs Identification of a Dps contamination in Mitomycin-C-induced expression of Colicin Ia.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H51 W52
Binding residue
(residue number reindexed from 1)		H40 W41
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0016722 oxidoreductase activity, acting on metal ions
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0006950 response to stress
GO:0030261 chromosome condensation
GO:0032297 negative regulation of DNA-templated DNA replication initiation
GO:0042594 response to starvation
Cellular Component
GO:0005737 cytoplasm
GO:0009295 nucleoid
GO:0016020 membrane
GO:1990084 DnaA-Dps complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aqs, PDBe:7aqs, PDBj:7aqs
PDBsum7aqs
PubMed33775657
UniProtP0ABT2|DPS_ECOLI DNA protection during starvation protein (Gene Name=dps)

[Back to BioLiP]