Structure of PDB 6nd4 Chain W Binding Site BS01

Receptor Information
>6nd4 Chain W (length=385) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYLLPESNGYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGP
YHIKYAKNGTHLLITGRKGHVASMDWRKGQLRAELFLNETCHSATYLQNE
QYFAVAQKKYTFIYDHEGTELHRLKQHIEARHLDFLPYHYLLVTAGETGW
LKYHDVSTGQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSM
PEPLVKLLSARGPVNSIAIDRSGYYMATTGADRSMKIWDIRNFKQLHSVE
SLPTPGTNVSISDTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPH
RNTPYMSHLFAGNKVENLGFVPFEDLLGVGHQTGITNLIVPGAGEANYDA
LELNPFETKKQRQEQEVRTLLNKLPADTITLDPNS
Ligand information
>6nd4 Chain 0 (length=408) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagacaagugcuugucguucguuaauggccucgucaaacgguggagaga
gucgcuaggugaucgucagaucugccuagucucuauacagcguguuuaau
ugacauggguugaugcguauugagagauauguuucuuuugcguuuaaccu
gaacagucucaucgugggcaucuuccauuggugagcagcgaaggauuugg
uggauuacuagcuaauagcaaucuauuucaaagaauucaaacuuggggga
augccuuguugaauauucuucaaguguaaccuccucucaaaucagcugau
uagaggaaacucaaagagugcuauggcggagugcgcuggucaagagugua
aaagcuuuuugaacagagagcauuuccgcagcagagauuucagcuguuuu
uuuuuuuu
<<<<<<<<<..>>>>>>.>>>............<<<<<<<<.<<...<<<
<..<<<<<<<.<<<....>>>..>>>>>>>>>>>...>>.>>>......>
>>>>..<<<<<<..<<<<<..<<<<<<<<>>>>>>>>.>>>>>.>>>>>>
.......<<<<<.<<<<.......>>>>..>>>>>...............
..........<<<...>>>.........................<<<<<.
..<<<<<<..<<<..>>>..>>>>.>>..>>>>>.....<<<<<..>>>>
>..........................<<<.<<<.<<<.<<<<<<<<...
...>>>>.>>>>.>>>...>>>..>>><<<<<.<<<..>>>.>>>>>...
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6nd4 Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		L224 K231 A232 P316 F355 G356 S357 M358 G359 G360 A374
Binding residue
(residue number reindexed from 1)		L161 K168 A169 P253 F292 G293 S294 M295 G296 G297 A311
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6nd4, PDBe:6nd4, PDBj:6nd4
PDBsum6nd4
PubMed31206356
UniProtP40055|UTP7_YEAST U3 small nucleolar RNA-associated protein 7 (Gene Name=UTP7)

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