Structure of PDB 5oqm Chain W Binding Site BS01

Receptor Information
>5oqm Chain W (length=258) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINKTE
LGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKVH
QVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCD
EPLVEDDSGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAANAL
EDEFEDVT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5oqm Chain W Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oqm Structures of transcription pre-initiation complex with TFIIH and Mediator.
Resolution5.8 Å
Binding residue
(original residue number in PDB)		C127 C149 C152
Binding residue
(residue number reindexed from 1)		C124 C146 C149
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006367 transcription initiation at RNA polymerase II promoter

View graph for
Biological Process
External links
PDB RCSB:5oqm, PDBe:5oqm, PDBj:5oqm
PDBsum5oqm
PubMed29088706
UniProtP36100|T2EA_YEAST Transcription initiation factor IIE subunit alpha (Gene Name=TFA1)

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