Structure of PDB 5nrl Chain W Binding Site BS01

Receptor Information
>5nrl Chain W (length=170) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFTPSIVIDAPQYYVDHFNGKYNVDKCVILRDLQLETDSESMPSSLKHL
TKPTHILDLTNNDLIMIPDLSRRDDIHTLLLGRNNIVEVDGRLLPMNVQN
LTLSNNSIRRFEDLQRLRRAPRTLKNLTLIGNQVCHLANYREHVLRLVPH
LETLDFQNVTAEERKSAMSF
Ligand information
>5nrl Chain 2 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaucucuuugaaguguaguaucuguucuuuucaguguaacaacugaaau
gaccuaggcucauacacauuuuuuggcaggacgggaagaggagacgucgc
gacccucgcacgagucguucuugacuuggucgcuugauguuucuucuucc
cguuc
Receptor-Ligand Complex Structure
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PDB5nrl Structure of a pre-catalytic spliceosome.
Resolution7.2 Å
Binding residue
(original residue number in PDB)		R92 R119 E152 N158 A161
Binding residue
(residue number reindexed from 1)		R92 R119 E152 N158 A161
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0030620 U2 snRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0005737 cytoplasm
GO:0071004 U2-type prespliceosome

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Cellular Component
External links
PDB RCSB:5nrl, PDBe:5nrl, PDBj:5nrl
PDBsum5nrl
PubMed28530653
UniProtQ08963|RU2A_YEAST U2 small nuclear ribonucleoprotein A' (Gene Name=LEA1)

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