Structure of PDB 2glj Chain W Binding Site BS01

Receptor Information

>2glj Chain W (length=456) Species: 1488 (Clostridium acetobutylicum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LLKEYKNAWDKYDDKQLKEVFALGDRFKNFISNCKTERECVTELIKTAEK
SGYRNIEDILAKGETLKEGDKVYANNRGKGLIMFLIGKEPLYTGFKILGA
HIDSPRLDLKQNPLYEDTDLAMLETHYYGGIKKYQWVTLPLAIHGVIVKK
DGTIVNVCVGEDDNDPVFGVSDILVHLASEQLEKKASKVIEGEDLNILIG
SIPLKDGEEKQKVKHNIMKILNEKYDISEEDFVSAELEIVPAGKARDYGF
DRSMVMGYGQDDRICAYTSFEAMLEMKNAKKTCITILVDKEEVGSIGATG
MQSKFFENTVADIMSDELKLRKALYNSEMLSSDVSAAFDPNYPNVMEKRN
SAYLGKGIVFNKYTGSRGKSGCNDANPEYIAELRRILSKESVNWQTAELG
KVDQGGGGTIAYILAEYGMQVIDCGVALLNMHAPWEISSKADIYETKNGY
SAFLNN

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

2glj Chain W Residue 6045 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2glj crystal structure of aminopeptidase I from Clostridium acetobutylicum
Resolution	3.2 Å
Binding residue (original residue number in PDB)	D265 E296 H441
Binding residue (residue number reindexed from 1)	D261 E292 H432
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.4.11.-

Gene Ontology

	Molecular Function
GO:0004177	aminopeptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:2glj, PDBe:2glj, PDBj:2glj
PDBsum	2glj
PubMed
UniProt	Q97K30\|APEA_CLOAB Probable M18 family aminopeptidase 1 (Gene Name=apeA)

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