Structure of PDB 2ez5 Chain W Binding Site BS01

Receptor Information
>2ez5 Chain W (length=46) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSGEEEPLPPRWSMQVAPNGRTFFIDHASRRTTWIDPRNGRAS
Ligand information
>2ez5 Chain P (length=11) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TGLPSYDEALH
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2ez5 Structural Determinants for High-Affinity Binding in a Nedd4 WW3(*) Domain-Comm PY Motif Complex
ResolutionN/A
Binding residue
(original residue number in PDB)
Q538 A540 N542 F546 I548 R553 R554 T555 T556 W557
Binding residue
(residue number reindexed from 1)
Q18 A20 N22 F26 I28 R33 R34 T35 T36 W37
Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
External links
PDB RCSB:2ez5, PDBe:2ez5, PDBj:2ez5
PDBsum2ez5
PubMed16531238
UniProtQ9VVI3|NEDD4_DROME E3 ubiquitin-protein ligase Nedd-4 (Gene Name=Nedd4)

[Back to BioLiP]