Structure of PDB 6gzx Chain V4 Binding Site BS01

Receptor Information
>6gzx Chain V4 (length=119) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIYKLIGRNLEITDAIRDYVEKKLARLDRYQDGELMAKVVLSLAGSPHVE
KKARAEIQVDLPGGLVRVEEEDADLYAAIDRAVDRLETQVKRFRERRYVG
KRHSYQGPPPPEVRDLEAL
Ligand information
>6gzx Chain A4 (length=1506) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
ccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucg
ugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguu
aguugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcg
ggaggaaggaggggacgacgucuggucagcauggcccuuacggccugggc
gacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacggg
gagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccg
accccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggu
gaauacguucccgggccuuguacacaccgcccgucacgccaugggagcgg
gcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggc
ccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggc
uggauc
....<<<<..[.(((..>>>>.<<<<.<<<<<..<<<<<<<......<<.
......<<<..<<...........................>>>>>.....
.<<.......<<<<<<<...<<...<<..<....<<<.......<<<...
...>>>........>>>.....<<<<..<<........>>..>>>>...<
<.......>>...>..>>..>>.>>>>>>><<<..........<<<<<<<
.......>>>>>>>..........>>>..<<<<<<<<....>>>...>>>
>>.>>..<.<<............>.>>..<<<<<..>>>>>.......>>
......<<.<<<.....<<......>>...>>>>>.>.>>>>>>..<<<<
......<.<<.....>>>.....>>>>....<<<<<........<<<...
...>.>>..........>>>>>......<<<<..(....<<<<<......
...)..........>>>>>.>>>>..>>>>>>>>>...........<<((
.....<<<<...<<<.<<<<<..<<<<<<<<.........<<<<<<....
.>>>>>>.......>>>>>..>>>.>>>>>..........<...<<<<<<
<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>........
...<......>.>>>>>>>..>...........>>>...>>>>....<<<
<<<...<<...<<<<.........>>>>...>>>>>>>>..........<
<<<<<..<<<<<.<<<<...>>>>.>>>>>...<<..))>>.....>>>>
>>.>>..........<<<<......>>>>.........))).].<.<..<
<<<<<<.....<<<<....<<<<<<<........<<........>>....
.......<<<............<......<.<............>>....
..................>........<<...<<<<.<..<.....<<<<
.<<<....>>>..<<<<......>>>>...>>>>........<<..<<.<
<....<....<.......>..>.....>>.>>..................
..........>>.......>...>.>...>>>.>>.........>>>...
....>>>>>>>......<<<.........<<...<<...<<.......>>
..>>.....>>.........>>>...........<<<<<<<........>
>>>>>>...........>>>>......<<<<<<..........>>>>>>.
...........>>>>>>>.>..>........<<...<<<<.<<<..<<.<
<<<..<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>..>>>
>.>>..>>>.>>>>....>>.........<<<<.<<<<....>>>>.>>>
>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gzx Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism.
Resolution4.57 Å
Binding residue
(original residue number in PDB)		K5 L6 I7 G8 R9 I13 R18 R30 L36 H49 E51 P63 G64 L66 R68 E70 R86 R93 R95 R97 Y99 G101 K102 R103 H104 Q107
Binding residue
(residue number reindexed from 1)		K4 L5 I6 G7 R8 I12 R17 R29 L35 H48 E50 P62 G63 L65 R67 E69 R85 R92 R94 R96 Y98 G100 K101 R102 H103 Q106
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0044238 primary metabolic process

View graph for
Biological Process
External links
PDB RCSB:6gzx, PDBe:6gzx, PDBj:6gzx
PDBsum6gzx
PubMed30301898
UniProtQ5SIS0

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