Structure of PDB 8x1c Chain V Binding Site BS01
Receptor Information
>8x1c Chain V (length=204) Species:
9606
(Homo sapiens) [
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KRPEGMHREVYALLYSDKKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEG
KDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRF
VVIHDRYDHQQFKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAG
HERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKL
ITAA
Ligand information
>8x1c Chain X (length=147) [
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acaggatgtatatatgtgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB
8x1c
Structure of nucleosome-bound SRCAP-C in the ADP-bound state
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
R49 R55
Binding residue
(residue number reindexed from 1)
R2 R8
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003714
transcription corepressor activity
GO:0005515
protein binding
GO:0061629
RNA polymerase II-specific DNA-binding transcription factor binding
Biological Process
GO:0000122
negative regulation of transcription by RNA polymerase II
GO:0006281
DNA repair
GO:0006325
chromatin organization
GO:0006338
chromatin remodeling
GO:0006355
regulation of DNA-templated transcription
GO:0042307
positive regulation of protein import into nucleus
GO:0042981
regulation of apoptotic process
GO:0045471
response to ethanol
GO:0045892
negative regulation of DNA-templated transcription
GO:0045893
positive regulation of DNA-templated transcription
GO:0051726
regulation of cell cycle
GO:1905168
positive regulation of double-strand break repair via homologous recombination
GO:2000779
regulation of double-strand break repair
Cellular Component
GO:0000786
nucleosome
GO:0000812
Swr1 complex
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005657
replication fork
GO:0005694
chromosome
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0035267
NuA4 histone acetyltransferase complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8x1c
,
PDBe:8x1c
,
PDBj:8x1c
PDBsum
8x1c
PubMed
38331872
UniProt
Q9NPF5
|DMAP1_HUMAN DNA methyltransferase 1-associated protein 1 (Gene Name=DMAP1)
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