Structure of PDB 8uua Chain V Binding Site BS01

Receptor Information
>8uua Chain V (length=90) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DARDIIKRPVVTEESTSILDDKKYTFEVDTRATKTQVKYAIEEIFDVKVA
KVNVMNYKGKLKRMGRYAGYTNKRRKAIVTVTADSKEIQF
Ligand information
>8uua Chain A (length=2894) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuagcgaauucagauaaacuccgaaugcc
auguacuuauacucgggagucagacugcgagugauaagauccguagucga
aagggaaacagcccagaccaccaguuaagguccccaaauauauguuaagu
ggaaaaggaugugggguugcuuagacaaccaggauguuggcuuagaagca
gccaccauugaaagagugcguaauagcucacuggucgagugaccccgcgc
cgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaaccuag
guucgugguaggagagcguucuaagggcggugaagucagaccggaaggac
ugguggagcgcuuagaagugagaaugccgguaugaguagcgaaagaaggg
ugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcucgucc
gcucaggguuagucgggaccuaagccgaggccgauaggcguaggcgaugg
acaacagguagagauuccuguaccagugcuaauuguuuaaccgauggggu
gacacagaaggauagggaaucgcacgaauggaaaugugcguccaagcagu
gagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugugaug
gggaagcggaaguuccugauuucacgcugucaagaaaagccucuaggaag
aguaguacugcccguaccgcaaaccgacacagguagaugaggagagaauc
cuaaggugagcgagagaacucucguuaaggaacucggcaaaaugaccccg
uaacuucgggagaaggggugcucuauuagggugcaagcccgagagagccg
cagugaauaggcccaggcgacuguuuagcaaaaacacaggucucugcaaa
accguaaggugacguauaggggcugacgccugcccggugcuggaagguua
agaggagugcuuagcuucggcgaagguacgaauugaagccccaguaaacg
gcggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaa
guuccgacccgcacgaaaggcgcaacgaucugggcacugucucaacgaga
gacucggugaaauuauaguaccugugaagaugcagguuacccgcgacagg
acggaaagaccccguggagcuuuacugcaaccugauauggaauguuugua
ccgcuuguacaggauagguaggagccgaagagacgugugcgcuagcauac
gaggaggcaauggugggauacuacccuggcuguaugaccauucuaacccg
ccacgcuaagcgcguggggagacagugucaggugggcaguuugacugggg
cggucgccuccuaaagaguaacggaggcgcccaaagguucccucagaaug
gauggaaaucauucgcagaguguaaaggcacaagggagcuugacugcgag
acugacaagucgagcagggacgaaagucgggcuuagugauccggugguuc
cgcauggaagggccaucgcucaacggauaaaagcuaccccggggauaaca
ggcuuaucucccccaagaguccacaucgacggggagguuuggcaccucga
ugucggcucgucgcauccuggggcuguagucggucccaaggguugggcug
uucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacag
uucggucccuauccgucgcgggcgcaggaaauuugagaggagcuguccuu
aguacgagaggaccgggauggacacaccgcugguguaccaguuguuccgc
caggagcaucgcuggguagcuauguguggcagggauaaacgcugaaagca
ucuaagcgugaagccccccucaagaugagauuucccauuucuucggaaag
uaagaucccugaaagaugaucagguagauagguuuggaguggaaguguag
cgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<........>>>>>>>>..>>.>.....>>
>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<<<<<<.......<<<<<.<<...<<<<.......>
>>>...>>.........<<......>>...>>>>>...>>>>>>>>>>.>
>...........))).....>>>>>>.>>>...>>>>>>><<<<<<<..>
>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>
>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<
.......>>>>>><<<<....<<<<<.<<<..<<<<<<...<<.....>>
.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>
...<<<<<........>>>>>))<<<<<<<<.<<......<<...<<<<<
...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<<<<<
..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>...>
>...........>>>>>...>>>...>>>>........>>>>>..>>..>
>.>>>>>>>>>>>>.>>>.....<<......>>>>>>>.<<<<.....>>
>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.
....<..>......>>>>><<<<<....<<<<....>>>>...>>>>>..
..........<<<<<<<<<..<<<.........>>>..<<<<<<<.....
<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..<<<<.
.<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>>>..>>>
>><<<<<<.......>>>>>>........<...........<<<<<<...
..>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>>>>>>
>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.((
(.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.<<<<<
<.<<<.<.........<<<<<..<<<.......<<<<<<<....>>>>>>
>....>>>............>>>>>>.>>>.>>>>>>.>>>>>....<<.
<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<....
.>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<
<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<
<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.(
(..>>>>..))>>>>>>>.............>>>>..]]>>>>.......
<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.....
..<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<..
...>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>
>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.
..............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.)
))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<.......
....>>>>>...>>>>.>>>>.......>>>>>>>..<<<<....>>>>.
...<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<.
...>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uua Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
T13 K24 T34 K35 Y40 K52 N54 M56 N57 Y58 K59 K61 M65 Y68 G70 N73 R76
Binding residue
(residue number reindexed from 1)
T12 K23 T33 K34 Y39 K51 N53 M55 N56 Y57 K58 K60 M64 Y67 G69 N72 R75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8uua, PDBe:8uua, PDBj:8uua
PDBsum8uua
PubMed38407413
UniProtA0A0U4MTC5

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