Structure of PDB 8ity Chain V Binding Site BS01

Receptor Information
>8ity Chain V (length=361) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RCPDCGSTELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNLREVTY
SRSTGENEQVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSG
IRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQ
IVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRTM
QLVELANETWLVTGRHPLPVITAATFLAWQSLQPADRLSCSLARFCKLAN
VDLPYPASSRLQELLAVLLRMAEQLAWLRVLRLDKRSVVKHIGDLLQHRQ
SLVRSAFRDLLLPPCMLKSPKRICPVPPVSTVTGDENISDSEIEQYLRTP
QEVRDFQRAQA
Ligand information
>8ity Chain X (length=82) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atatgcttaccgtaacttgaaagtatttcgatttcttggctttatatatc
ttgtggaaaggacgaaacaccgtgctcgcttc
Receptor-Ligand Complex Structure
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PDB8ity Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S68 R110 L111 Q267
Binding residue
(residue number reindexed from 1)		S63 R105 L106 Q262
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0005515 protein binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006359 regulation of transcription by RNA polymerase III
GO:0034599 cellular response to oxidative stress
GO:0070897 transcription preinitiation complex assembly
Cellular Component
GO:0000126 transcription factor TFIIIB complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0097550 transcription preinitiation complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8ity, PDBe:8ity, PDBj:8ity
PDBsum8ity
PubMed37165065
UniProtQ9HAW0|BRF2_HUMAN Transcription factor IIIB 50 kDa subunit (Gene Name=BRF2)

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