Structure of PDB 7tql Chain V Binding Site BS01

Receptor Information
>7tql Chain V (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTR
KTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTI
A
Ligand information
>7tql Chain 2 (length=1656) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacg
ccggcggcgacgacccauucgaacgucugcccuaucaacuuucgauggua
gucgccgugccuaccauggugaccacgggugacggggaaucaggguucga
uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca
ggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaa
caauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaa
uccuuuaacgaggauccauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcuc
guaguuggaucucuagcguuuacuuugaaaaaauuagaguguucaaagca
ggccgccuggauaccgcagcuaggaauaauggaauaggaccgcgguucua
uuuuguugguuuucggaacugaggccaugauuaagagggacggccggggg
cauucguauugcgccgcuagaggugaaauucuuggaccggcgcaagacgg
accagagcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaa
gucggagguucgaagacgaucagauaccgucguaguuccgaccauaaacg
augccgaccggcgaugcggcggcguuauucccaugacccgccgggcagcu
uccgggaaaccaaagucuuuggguuccggggggaguaugguugcaaagcu
gaaacuuaaaggaauugacggaagggcaccaccaggaguggagccugcgg
cuuaauuugacucaacacgggaaaccucacccggcccggacacggacagg
auugacagauugauagcucuuucucgauuccgugggugguggugcauggc
cguucuuaguugguggagcgauuugucugguuaauuccgauaacgaacga
gacucuggcaugcuaacuaguuacgcgaccggucggcguaacuucuuaga
gggacaaguggcguucagccacccgagauugagcaauaacaggucuguga
ugcccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcg
uguccuacgccggcaggcgcggguaacccguugaaccccauucgugaugg
ggaucggggauugcaauuauuccccaugaacgaggaauucccaguaagug
cgggucauaagcuugcguugauuaagucccugcccuuuguacacaccgcc
cgucgcuacuaccgauuggaugguuuagugaggcccucggaucggccccg
ccggggugcccuggcggagcgcugagaagacggucgaacuugacuaucua
gaggaaguaaaagucguaacaagguuuccguaggugaaccugcggaagga
ucauua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<<....>>>>>>..
.>>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<
<..>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<....<<<<<<
<.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>..
..>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>
>>>.........<<<....<<<<...>>>>..>>>..>...>>.>.....
<<<....<<.<<<....>>>..>>.....>>>......<<..<.......
....>..>>.........<<<<<((......<<<<.....<<..))>>..
.....>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<
...<<<.<<...<..>...<<<<<<.<.......<<...<.......>..
<<<.>>>....>>......>.>>>..>>>........<.<<.<<<<<<<.
..............>>>>>>>.>>.>....>>....<<<<<<..<...<<
<<..<<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>.
......<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....
<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>........
..<<<.<<.<<<..<.<<<<<<.<<<<<....>>>>>>>>>>>.>..>>>
...<<..))>>...>>.....>>>.>.>.<<<......<<<<....>>>>
....>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<.
<......<<........>>..........<<<<<......<<<<<<....
...<<.<<<........>>>.>>.....>>>>>>...<..<<<..<<.<<
<<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>..
..<<<...<...<<<<..<<<<<<<<<<<..>>>.>>>>>>>>..>>>>.
.>.....<<<<<.....>>>>>........>>>....>>>.>>>.....>
>>>>.>.......>>>>>...>..>>>>.>>>.....<<.<<<.......
.<.<<<.<<<<....>>>>.>>>....>.........>>>.>>.......
.....<<<<<..........>>>>>...........>>>>>.....<<<<
<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..
<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<<<<<
<<<<<<..>>>>>>>>>.>.>>>>>...>>.>>>>..>>>.>>>>>>>>.
..>>.>>>>...>.>>...>.....<<<<<<<<<....>>>>>>>>>...
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7tql eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		V29 E33 R55 M56 P57 T58 K59 T65 R66 K67 T68 P69 C70 G71 E72 G73 S74 K75 T76 W77 R79 R83 K86 R87 L88
Binding residue
(residue number reindexed from 1)		V13 E17 R39 M40 P41 T42 K43 T49 R50 K51 T52 P53 C54 G55 E56 G57 S58 K59 T60 W61 R63 R67 K70 R71 L72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7tql, PDBe:7tql, PDBj:7tql
PDBsum7tql
PubMed35732735
UniProtP60866|RS20_HUMAN Small ribosomal subunit protein uS10 (Gene Name=RPS20)

[Back to BioLiP]