Structure of PDB 7pnt Chain V Binding Site BS01

Receptor Information
>7pnt Chain V (length=365) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLSAAYVDSHQWEAREKEEYHLADLASLMDKAYERKLPVSSLSISRFVDN
IASREDLDSAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKYGAQDKALYT
LVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDALSVVFEIMMQEAFDVPST
QFLSLYVLYRCLAEKTELTWEEERDFGASLLLSGLKQRNTVGLSSQLYGY
ALLGKVELQRGVRAVYHGMPLMWTPGYLDRALQVMERVASSPEDLKLGRE
VLDVLDGVLKVVTSPDGSANLVEQLDTEEPEQSKLPRYLERFQASRSKLQ
ELNRVESESLLTLTTQLVKEKLPACEAEDLATYEQKLREWHLERVQLIQR
EQEQREKAKQEYQAL
Ligand information
>7pnt Chain A (length=909) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaagguuugguccuggccuuauaauuaauuagagguaaaauuacacaugc
aaaccuccauagaccgguguaaaaucccuuaaacauuuacuuaaaauuua
aggagaggguaucaagcacauuaaaauagcuuaagacaccuugccuagcc
acacccccacgggacucagcagugauaaauauuaagcaauaaacgaaagu
uugacuaaguuauaccucuuaggguugguaaauuucgugccagccaccgc
ggucauacgauuaacccaaacuaauuaucuucggcguaaaacgugucaac
uauaaauaaauaaauagaauuaaaauccaacuuauaugugaaaauucauu
guuaggaccuaaacucaauaacgaaaguaauucuagucauuuauaauaca
cgacagcuaagacccaaacugggauuagauaccccacuaugcuuagccau
aaaccuaaauaauuaaauuuaacaaaacuauuugccagagaacuacuagc
cauagcuuaaaacucaaaggacuuggcgguacuuuauauccaucuagagg
agccuguucuauaaucgauaaaccccgcucuaccucaccaucucuugcua
auucagccuauauaccgccaucuucagcaaacccuaaaaagguauuaaag
uaagcaaaagaaucaaacauaaaaacguuaggucaagguguagccaauga
aaugggaagaaaugggcuacauuuucuuauaaaagaacauuacuauaccc
uuuaugaaacuaaaggacuaaggaggauuuaguaguaaauuaagaauaga
gagcuuaauugaauugagcaaugaaguacgcacaccccuccuaaauuaaa
cuuaacauaauuaauuucuacguuuauggagauaaaagcauacugagugu
gcuuggaau
..((((..<<<<<<.)))).<<<<<<<.<..<<<<<<<<....<<<.<<<
..<......>......<<......<<<<<<<<<..<<<....>>>.>>>>
>>>.>>.<<<....<<...<<....>>..>>......>>>..<<...>>.
>>.<<<....>>>.....>>>>>>..........<<....<<<<....>>
>>..>>...>>.>>>>>>...<<<<<<<<.....(((.....((.>>>))
.......)))..>>>>>..>.>>>>>>>....<<<((.....<<<<....
<<............<<<<<<....<<<<<<<....<<......>>.....
>>>.>>>..>..........<<....>>.>>>>>>......>>....>>>
>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>...
.......<<<<.<<.......))..>>.>>>>.>>>.<<<.......<<<
....>>>.....>>>..>>>>>>.<<<<...<<<<........<<<<<..
<<<<<<<<<<.....<<........>>..........<<<<.<<......
.....<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>
>..>>......<<.....>>..........>>>...>>>>>>>>....>>
.>>>>..>>.>>>>>>>>.....<<<<<....>>>>>.....<<..<.<<
<<<<......>>>>>>..>.>>.....>>>>>.....<<<<<<<......
...>>>>>>>............>>>>..>>>.>....<<<<<<<<<....
......<<.....>>......>>>>>.>>>>....<<<<<<<<<.>>>>>
>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pnt Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Resolution3.19 Å
Binding residue
(original residue number in PDB)		K64 P66 S68 S69 W102 Y103 E386 R393 Q397 E404 Y405 L408
Binding residue
(residue number reindexed from 1)		K36 P38 S40 S41 W74 Y75 E343 R350 Q354 E361 Y362 L365
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0097177 mitochondrial ribosome binding
Biological Process
GO:0006417 regulation of translation
GO:0008283 cell population proliferation
GO:0032543 mitochondrial translation
GO:0070131 positive regulation of mitochondrial translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7pnt, PDBe:7pnt, PDBj:7pnt
PDBsum7pnt
PubMed35676484
UniProtQ8BK72|RT27_MOUSE Small ribosomal subunit protein mS27 (Gene Name=Mrps27)

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