Structure of PDB 7dvq Chain V Binding Site BS01

Receptor Information
>7dvq Chain V (length=468) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLS
RSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRN
DKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLK
ECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFK
DHPIILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKY
KAIKKEILQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEF
PESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKE
QYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRI
FVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFF
TSIGLGGLTDELREHLKN
Ligand information
>7dvq Chain U (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MYNGIGLPTPRGSGTNGYVQRNLSLV
Receptor-Ligand Complex Structure
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PDB7dvq Structure of the activated human minor spliceosome.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		H474 K478 R513
Binding residue
(residue number reindexed from 1)		H293 K297 R332
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0048024 regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005829 cytosol
GO:0016607 nuclear speck
GO:0071005 U2-type precatalytic spliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7dvq, PDBe:7dvq, PDBj:7dvq
PDBsum7dvq
PubMed33509932
UniProtQ9HCG8|CWC22_HUMAN Pre-mRNA-splicing factor CWC22 homolog (Gene Name=CWC22)

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