Structure of PDB 6lab Chain V Binding Site BS01

Receptor Information
>6lab Chain V (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVG
ENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTK
KEIKKVATP
Ligand information
>6lab Chain J (length=169) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
cagctctagcaccgcttaaacgcacgtacggattccgtacgtgcgtttaa
gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
gtgaaaaaaaaaagctgca
Receptor-Ligand Complex Structure
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PDB6lab Engineering nucleosomes for generating diverse chromatin assemblies.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q37 K40
Binding residue
(residue number reindexed from 1)		Q26 K29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003680 minor groove of adenine-thymine-rich DNA binding
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031490 chromatin DNA binding
GO:0031491 nucleosome binding
GO:0031492 nucleosomal DNA binding
Biological Process
GO:0006334 nucleosome assembly
GO:0030261 chromosome condensation
GO:0031507 heterochromatin formation
GO:0045910 negative regulation of DNA recombination
GO:2000679 positive regulation of transcription regulatory region DNA binding
Cellular Component
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0000791 euchromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005794 Golgi apparatus
GO:0015629 actin cytoskeleton
GO:0016604 nuclear body
GO:0017053 transcription repressor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lab, PDBe:6lab, PDBj:6lab
PDBsum6lab
PubMed33590100
UniProtP07305|H10_HUMAN Histone H1.0 (Gene Name=H1-0)

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