Structure of PDB 6bvb Chain V Binding Site BS01
Receptor Information
>6bvb Chain V (length=151) Species:
9606
(Homo sapiens) [
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PRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRR
IHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTL
KERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAH
Q
Ligand information
>6bvb Chain H (length=14) Species:
9606
(Homo sapiens) [
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ETLAPYIPMDGEDF
Receptor-Ligand Complex Structure
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PDB
6bvb
HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease.
Resolution
2.002 Å
Binding residue
(original residue number in PDB)
N67 R69 I75 W88 F91 Y98 P99 G106 H110 S111 Y112 H115 W117
Binding residue
(residue number reindexed from 1)
N9 R11 I17 W30 F33 Y40 P41 G48 H52 S53 Y54 H57 W59
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6bvb
,
PDBe:6bvb
,
PDBj:6bvb
PDBsum
6bvb
PubMed
30135421
UniProt
P40337
|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)
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