Structure of PDB 5oql Chain V Binding Site BS01

Receptor Information
>5oql Chain V (length=121) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAAWPKAEDPALVQELLDCVQQASHYRQLKKGANETTKSVNRGTSELVIL
AADTQPLSIVLHIPLICEEKNVPYVYVPSKVALGRACGVSRAVIAVSLTS
NEASDLNSKIRALRDKVERLA
Ligand information
>5oql Chain 1 (length=1350) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucuccgcggcagcgcaagccg
uuucauacgucgccgcaaucgcgaggggcuccaagcggucgccggcgagc
accaccccagccccgcgccgcccccagcgcaccgcgcgcaggggggccgg
cgcggcaucugggaagacuccuaaggcgcaagggaauaccccgugcgccg
gggguugggcucugugggugcuuggccgcuggccagaccuacuucaaagc
caccggggguaccuaccgguugucucggucgggccuccucuuggggcgcc
uaggcggugucuucgggucgcgugcagccucccguccucgccugccgaca
gcgcucuggggaauucaggaggggaaagcagaugugccccgcggcgagac
uggcgccggacgagcugcuggggcacgcggguacgcuagccgcacgauag
uuaccugguugauucuuagucauaugcuugucucaaagccaugcgucuaa
guauaagcaauuacagcgaaacugcgaauggcucauuaaaucaguuaucg
uuuauuugauaguauggauaaccgugguaauucuagagcuaauacaugcg
uauuuauuagggugauucauaauaacuucucgaaucgcacggccuugcgc
cggcgaugguucauucaaauuucugcccuaucaacuuucgacggcugggu
auuggccagccguggugacaacggguaagagaggagccugagaaacggcu
acuacauccaaggaagggcaggcgccaaauuacccaaucccgacacgggg
agguagugacaauaaauacugauacagggcuccgggucuuguaauuggaa
ugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucugg
ugccagcagccgcgguaauucccuccaauagcguauauugcucguaguug
aaccugauuaauagggacagucgggggcgucaguauucaauugucagagg
ugaaauucuuggauuuauugaagacuaacaacugcgaaagcauucgccaa
ggauguuuucauuaaucaggaacgauuagggaucggacggcguuuauuuu
ugacccguucggcaccuuacgauaaaucaaaauguuugggaguauggucg
caugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
<<.<<<.<<<<<<<<....>>>>>>>>>>>.>.>.<<<<.<..>..>>>>
.........<<<<<<<.<<<<<..<<<<>>>>..>>>>>.>>.>>>>>..
..<..<<<<<..<<<<<<<<<<<<<.<<<<.....>>>>..>>>>>.>>>
>>>>>...>>>>>..>........<<<<<<.<<<.....>>>.>>>>>>.
........................<<<...>>>.................
....<<<<<..<<<<<<<<.....>>>>>.>>>>>>>>.....<<<<<<.
..<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>....
>>>>>>...........................<<<<.<<<<<<<..<.<
<<<..>>>>.>..>>>>>.>>.>>>><<<<.<.....>.>>>>.......
..................<..<<<<<<...<.<<..<<<<.<<<<<....
<<....<<.......>>...>>.>>......<<<.......<<<..<<..
<<....<<<.......<.<..<..<<<.....>>>..>.....>>....<
...<<<<<<.<......>.>>>>>>.....>...<<<<.<<<<.....>>
>>>>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<..
.....>>>>>>>>>>>......>>>...>>><<.<<<..........>>>
.>>.<.<<<..>>>.>.>>>>>>........<<<...<<<<<...>>>>.
>>>>..>>...>.>....<<<<<<<<<<<<<...>>>>>>>>.>>>>>..
...<<..<...........>..>>.........<<<<<<.......<<<.
...>>>................>>>>>>..>>>>>>.>.<.<<...<<<.
<<.....>>.....<<<<<.<<...<<<<..<<<.<<<<<<.....<<<.
.....>>>........>>>>>>.>>>.......<<....>>...>>>>..
>>.>>>.>>....>>>...>>.>..<..<<..<<<<<<<<.<<<......
.>>>>>>>>>>>..>>.....<....>....>..................
..<<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>>.<<<<.<<......>>.>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5oql 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D110 K114
Binding residue
(residue number reindexed from 1)		D105 K109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0000470 maturation of LSU-rRNA
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005730 nucleolus
GO:0022625 cytosolic large ribosomal subunit
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071011 precatalytic spliceosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5oql, PDBe:5oql, PDBj:5oql
PDBsum5oql
PubMed28967883
UniProtG0SGM0

[Back to BioLiP]