Structure of PDB 4y80 Chain V Binding Site BS01
Receptor Information
>4y80 Chain V (length=222) Species:
559292
(Saccharomyces cerevisiae S288C) [
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TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAA
DTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIV
AGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEE
AIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ
KSYKFPRGTTAVLKESIVNICD
Ligand information
>4y80 Chain f (length=3) Species:
32630
(synthetic construct) [
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LAI
Receptor-Ligand Complex Structure
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PDB
4y80
Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
T1 S20 T21 Q22 K33 G47 A49
Binding residue
(residue number reindexed from 1)
T1 S20 T21 Q22 K33 G47 A49
Enzymatic activity
Catalytic site (original residue number in PDB)
T1 D17 R19 K33 G47 S129 D166 S169
Catalytic site (residue number reindexed from 1)
T1 D17 R19 K33 G47 S129 D166 S169
Enzyme Commision number
3.4.25.1
: proteasome endopeptidase complex.
Gene Ontology
Molecular Function
GO:0004298
threonine-type endopeptidase activity
Biological Process
GO:0051603
proteolysis involved in protein catabolic process
Cellular Component
GO:0005839
proteasome core complex
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Cellular Component
External links
PDB
RCSB:4y80
,
PDBe:4y80
,
PDBj:4y80
PDBsum
4y80
PubMed
26020686
UniProt
P25043
|PSB2_YEAST Proteasome subunit beta type-2 (Gene Name=PUP1)
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