Structure of PDB 6zqb Chain UX Binding Site BS01

Receptor Information
>6zqb Chain UX (length=174) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKFGLVKRTLNTKKDQRLKKNQENTRNIPQVSSALFFQYNQAIKPPYQV
LIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRI
ALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIR
KIPGIPLMSVGGHAYVIEKLPDVF
Ligand information
>6zqb Chain D2 (length=522) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucgu
caaacgguggagagagucgcuaggugaucgucagaucugccuagucucua
uacagcguguuuaauugacauggguugaugcguauugagagauacaauuu
gggaagaaauucccagaguguguuucuuuugcguuuaaccugaacagucu
caucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggugg
auuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaaug
ccuuguugaauagccggucgcaagacugugauucuucaaguguaaccucc
ucucaaaucagcgauaucaaacguaccccgugaaacaccgggguaucugu
uugguggaaccugauuagaggaaacucaaagagugcuaugguauggugac
ggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcauuucc
ggcagcagagauuucagcuguu
<<<....>>>...<<<<<<<<<..>>>>>>.>>>..............<<
<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>.
..>>.>>>......>>>>>..<<<<<...<<<<<..<<<<<.<<<<.<<<
<<<<<....>>>>>>>>.>>>>.>>>>>.>>>>>..>>>>>.......<<
<<<<<<<<<...........>>>>>.>>>>>>..................
.......<<<...>>>.........................<<<<<..<<
<<<<<..<<<....<<<<<....>>>>>...>>>..>>>>.>>.>>>>>>
.....<<<<<<....<<<<<<<.<<<<<<<........>>>>>>>...>>
>>>>>.....>>>>>>.................................<
<<<<<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>>.>>>
><<<<<.<<<..>>>.>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqb 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		V13 K21
Binding residue
(residue number reindexed from 1)		V7 K15
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004521 RNA endonuclease activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zqb, PDBe:6zqb, PDBj:6zqb
PDBsum6zqb
PubMed32943521
UniProtQ05498|FCF1_YEAST rRNA-processing protein FCF1 (Gene Name=FCF1)

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