Structure of PDB 6woo Chain UU Binding Site BS01

Receptor Information
>6woo Chain UU (length=106) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQQQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLK
ISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDV
EVVVAS
Ligand information
>6woo Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguug
gccggucgauuuuccaacggggccuuuccuucuggcuaaccuugaguccu
uguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcguauugcucgaauauauuagcauggaauaauagaauaggac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuu
aaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugaccc
acucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaug
gucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagu
ggagccugcggcuuaauuugacucaacacggggaaacucaccagguccag
acacaauaaggauugacagauugagagcucuuucuugauuuugugggugg
uggugcauggccguucuuaguugguggagugauuugucugcuuaauugcg
auaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugg
uuauccacuucuuagagggacuaucgguuucaagccgauggaaguuugag
gcaauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcu
acacugacggagccagcgagucuaaccuuggccgagaggucuugguaauc
uugugaaacuccgucgugcuggggauagagcauuguaauuauugcucuuc
aacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguc
ccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuag
ugaggccucaggaucugcuuagagaagggggcaacuccaucucagagcgg
agaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagg
uuuccguaggugaaccugcggaaggaucau
..<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<..<<..<<....<<<................<<......<<.
<<<.....>>>.>>......>>........<<<<<............>>>
>><...<<<<<<......((((((..<<<....>>>....<<......>>
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<..<......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>
>>>.........<<<[[.....<.<<...<<<........<<<<<.<<<<
.....<..>.....>>>>.>>>>>......<<<<.....<<....<<...
....>>....>>.....>>>>....<<<<<.<<.......<<...<....
...>..<<<.....>>>....>>......>>.>>..>>>.........<<
<..<<<<<<<<......)))))).>>>>>>>>.>>>...........<<<
<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.
>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>
...>>.>....<<<<<.....<...<<<<.<.....>.>>>>...>..>>
>>>..........<<<.<<..<<..<<<<<<<<.<<<........>>>>>
>>>>>>..>>....<<..]]>>...>>.....>>>.>>>.<<<......<
<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<
..<<<.<<<<<<......<<........>>..........<<<<<.....
.<<<<<........<<.<<<........>>>.>>......>>>>>...<<
.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<......>>>
...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>
>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>
>....>>>.>>>...>.>>>>>>>.......>>>>>...>>.>>>>.>>>
.....<<<<<<<......<<.....<<..<<<<....>>>>..>>....>
>.......>>>>>>>...........<<<<<<..........>>>>>>..
........>>>>>>....<<<<<<<<.......>>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<
<..<.<<..<...<<<<<............................>>>>
>...>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>....
.<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6woo An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
R23 E35 K53 G54 V56 R57 L58 P59 K61 K64 S66 T67 R68 K69 P71 N72 G73 E74 G75 S76 K77 T78 W79 R85 H87 K88 R89 Y90
Binding residue
(residue number reindexed from 1)
R9 E21 K39 G40 V42 R43 L44 P45 K47 K50 S52 T53 R54 K55 P57 N58 G59 E60 G61 S62 K63 T64 W65 R71 H73 K74 R75 Y76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6woo, PDBe:6woo, PDBj:6woo
PDBsum6woo
PubMed
UniProtP38701|RS20_YEAST Small ribosomal subunit protein uS10 (Gene Name=RPS20)

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