Structure of PDB 6rxz Chain US Binding Site BS01

Receptor Information
>6rxz Chain US (length=451) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKWSLAAAEALCRVFVRLLAAGTIINWLRDRLSDYDGVLLSMLQSLAVHA
LVLAMAVLKAQAQHLTDREEAIFPRSFFLEIIAVVLESPIEHLRGHFSEN
FVKKYDDIRFYTFEAIKHFLTEEDVRNNVFNLLLSIEDVPESNDSLENFF
IERPPKKKHPLLSLSQHKKQAQEAWLAFMHLGLSKEQRKKVLEVMSASIA
PWFTKPEMLMDFLTDCYNSGGSVSLLALSGVFYLIQERNLDYPEFYTKLY
SLLDADILHSKYRSRFFRLLDTFLASTHLPAVLVASFIKRLARLALNAPP
SAIVVIVPWFYNLFKKHPLTTFMMHRVPRTKEEREKLEKDGLDDPFLPNE
TDPMETRAIDSCLWEIVQLQSHYHPNVATICKIISEQFTKQAYNLEDFLD
HSYGSLLEAEMTKEVKKPPVIEFMIPKHIFTKAAPEEEKKDSLLVSLWDF
G
Ligand information
>6rxz Chain C1 (length=1487) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucucccggcagccuucgcggg
cagccguagucccgguucauacgucgccgcaaucgcgaggggaccaacgg
guaaccguuccuccaagcggucgccggcgagcaccaccccagccccgcgc
cgcccccagcgcaccgcgcgcaggggggccggcgcggcaucugggaagac
uccuaaggcgcaagggaauaccccgugcgccggggguugggcucuguggg
ugcuuggccgcuggccagaccuacuucaaagccaccggggguaccuaccg
guugucucggucgggccuccucuuggggcgccuaggcggugucuucgggu
cgcgugcagccucccguccucgccugccgacagcgcucuggggaauucag
gaggggaaagcagaugugccccgcggcgagacuggcgcaccgccggacga
gcugcuggggcacgcggguacgcuagccgcacgauaguuaccugguugau
ucugcuagucauaugcuugucucaaauaagccaugcgucuaaguauaagc
aauuacagcgaaacugcgaauggcucauuaaaucaguuaucguuuauuug
auaguaccuuacuauggauaaccgugguaauucuagagcuaauacaugca
aaaucccgacuucggaagggauguauuuauuagagcccuucggggcggug
auucauaauaacuucucgaaucgcacggccuugcgccggcgaugguucau
ucaaauuucugcccuaucaacuuucgacggcuggguauuggccagccgug
gugacaacggguaaggguuagggcucggagaaggagccugagaaacggcu
acuacauccaaggaagggcaggcgcgcaaauuacccaaucccgacacggg
gagguagugacaauaaauacugauacagggcucuuucgggucuuguaauu
ggaaugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagu
cuggugccagcagccgcgguaauuccagcuccaauagcguauauugcucg
uaguugaaccugauuaauagggacagucgggggcgucaguauucaauugu
cagaggugaaauucuuggauuuauugaagacuaacaacugcgaaagcauu
cgccaaggauguuuucauuaaucaggaacgauuagggaucggacggcguu
uauuuuugacccguucggcaccuuacgauaaaucaaaaggaguauggucg
caaggcugaaaaauugacggaagggcaccaccagggguggagccugcgcg
cgcgcuacacugacagagccagcgaguacucccuuggccgagaggcccgg
guaaacucugucgugcugaggaaucccuaguaagcgcaagucaucagcuu
gcguugauuacgucccugcccuuuguacacaccgcccgucgcuacuaccg
auagaggaaguaggucuccguaggugaaccugcggag
<<<<<<.<<.<<<<<....>>>>>.>>.>>>>>><<<<.<<<<....>>>
>.>>>>.................<<<<<<<.<<<<<..<<<<...<<<<<
....>>>>>.>>>>..>>>>>.>>.>>>>>.......<<<<<..<<<<<<
<<<<<<<.<<<<.....>>>>..>>>>>.>>>>>>>>...>>>>>.....
......<<<<<<.<<<.....>>>.>>>>>>...................
......<<<...>>>.....................<<<<<..<<<<<<<
<.....>>>>>.>>>>>>>>.....<<<<<<...<<<<<<<....<<<<.
.<<.....>>..>>>>....>>>>.>>>....>>>>>>............
...............<<<<<<<<<<<<..<.<<<<<.....>>>>>.>..
>>>>>.>>>>>>><<<<.........>>>>....................
.......<<.<<<<<<...<.<<..<...<<<.<<<<<....<<....<<
.......>>...>>.>>......<<<.......<<<..<<..<<....<<
<.............<<..<..<..<<<.....>>>..>.....>>>....
..<<<<<..........>>>>><...<<<<<<..<<<<....>>>>....
.....>>>>>>.....>...<<<<.<<<<.....>>>>>>>>....>>>.
..>>>>..>>>.<<<....<<.....<<<<<<<<.......>>>>>>>>.
>>......>>>...<<<......>>>.>>>.<<.<<<<........>>>>
.>>.<.<<<..>>>.>.>>>>>>.........<<<....<<<<...>>>>
..>>>..>>...>.>....<<<<<<<<<<<<<<....>>>>>>>>>.>>>
>>.....<<..<...........>..>>.........<<<<<<.......
<<<....>>>..................>>>>>>..>>>>>>>>.<.<<.
..<<<.<<.....>>....<<.<<<.<<...<<<<..<<<.<<<<<<...
..<<<......>>>........>>>>>>.>>>.......<<....>>...
>>>>..>>.>>>..>>...>>>...>>.>.....<<..<<<<<<<<.<<<
.......>>>>>>>>>>>..>>.....<....>.................
...............<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>
>>.>>>.....<<<<<<<..............<<.<<<<....>>>>.>>
.....>>>>>>>..........>>>>>>....<<<<<<<.........>>
>>>>>......>>...>>>>>>>............>>>>>..<<<<.<<.
.....>>.>>>>...<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxz Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		R156 E158 R163 S259 Q260 K263
Binding residue
(residue number reindexed from 1)		R68 E70 R75 S165 Q166 K169
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0030692 Noc4p-Nop14p complex
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxz, PDBe:6rxz, PDBj:6rxz
PDBsum6rxz
PubMed31378463
UniProtG0RZL4

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