Structure of PDB 7aju Chain UQ Binding Site BS01

Receptor Information
>7aju Chain UQ (length=820) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYKLSVVSGGKPALNNLSSVTGNKNIARLSQDQRNYIIPFNNQIKVYSVE
TRQCVKTLKFANNSLLSGIFLQEEENNESIVKILLGDITVPQQAHLITVF
TNNGHVIVLNYKGKLVESPKHFKISLADEKLANVFHSEGNYRILTTFKDN
SLQSYRLYALTFDDAKKQFEVAHQAEWHNVILSNISSNGKLLAHMCKDVS
TKDHEHKSISVVSLFDDSVNLSFPLGSILSSQTQSLSYNTRYVSSMAIDN
MGQQLAVGFASGVISIVSLADLQIRLLKWHIDSVLSLSFSHDGSYLLSGG
WEKVMSLWQLETNSQQFLPRLNGIIIDCQVLGPQGNYYSLILQMTENNSN
SDYQFLLLNASDLTSKLSINGPLPVFNSTIKHIQQPISAMNTKNSNSITS
LNHSKKKQSRKLIKSRRQDFTTNVEINPINKNLYFPHISAVQIFDFYKNE
QVNYQYLTSGVNNSMGKVRFELNLQDPIITDLKFTKDGQWMITYEIEYPP
NDLLSSKDLTHILKFWTKNDNETNWNLKTKVINPHGISVPITKILPSPRS
VNNSQGCLTADNNGGLKFWSFDSHESNWCLKKISLPNFNHFSNSVSLAWS
QDGSLIFHGFDDKLQILDFDTFKKFESLENTKTVSEFTLDSEIQTVKLIN
DTNLIVATRTTLNAINLLRGQVINSFDLYPFVNGVYKNGHMDRLITCDER
TGNIALVINQQLTDVPTINYKSRIIIFDSDLSTKLGNFTHHEYISWIGWN
YDTDFIFLDIESTLGVVGTNDEDEEDIALEFINGEKKDKLVNMNSFTSMF
DNIQNVQMDTFFDRVMKVLT
Ligand information
>7aju Chain D2 (length=81) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucgu
cggauuugguggaaggaaacucaaagagugc
<<<....>>>...<<<<<<<<<..>>>>>>.>>>................
...............................
Receptor-Ligand Complex Structure
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PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		N166 S167 L168 I197 H220 H222 K223 Q248 T249 L252 S253 Y254 Y258 V259 F275 V279 K294 W295 I297 E318 V320 Q332 F333 P335 I414 T415 R426 K427 K430 R433 G482 V484 S554 P556 F607 S608 N609
Binding residue
(residue number reindexed from 1)		N150 S151 L152 I181 H204 H206 K207 Q232 T233 L236 S237 Y238 Y242 V243 F259 V263 K278 W279 I281 E302 V304 Q316 F317 P319 I398 T399 R410 K411 K414 R417 G466 V468 S538 P540 F591 S592 N593
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:2000234 positive regulation of rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005777 peroxisome
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0033553 rDNA heterochromatin
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtQ02931|UTP17_YEAST NET1-associated nuclear protein 1 (Gene Name=NAN1)

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